A paradigm shift: AUC as a multi-attribute platform method in targeted protein degradation

Discover how Analytical Ultracentrifugation (AUC) is transforming targeted protein degradation (TPD) research and enabling deeper insights into ternary complex formation.

In this webinar, Dr. Alexander Yaritzky (Bioanalysis) explains how AUC can be used to characterize protein interactions, quantify ternary complexes, and support drug discovery for emerging therapeutic modalities.

Key topics covered:
- What is targeted protein degradation (TPD) and how it differs from traditional therapeutics
- How PROTACs and molecular degraders form ternary complexes
- Using AUC to measure affinity, stoichiometry, and kinetics
- Advantages of label-free, solution-based analysis
- Understanding the hook effect and ternary complex dynamics
- Applying AUC for screening and characterization workflows

This session is ideal for scientists working in:
Biopharma research
Drug discovery
Protein characterization
Structural biology

Learn how to integrate AUC into your workflow for more accurate, high-confidence data in complex biological systems.

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#AUC #ProteinDegradation #PROTAC #Biopharma #DrugDiscovery #AnalyticalUltracentrifugation

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