Gigantism, Causes, Signs and Symptoms, Diagnosis and Treatment

Gigantism (Greek γίγας, gígas, "giant", plural γίγαντες, gígantes), also known as giantism, is a condition characterized by excessive growth and height significantly above average. In humans, this condition is caused by over-production of growth hormone[2] in childhood, resulting in people 2.1 to 2.7 m (7 to 9 ft) in height.[3][4][5][6]

It is a rare disorder resulting from increased levels of growth hormone before the fusion of the growth plate which usually occurs at some point soon after puberty. This increase is most often due to abnormal tumor growths on the pituitary gland.[7][8] Gigantism should not be confused with acromegaly, the adult form of the disorder, characterized by somatic enlargement specifically in the extremities and face.

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