Do We Have to Get Old and Die?

We’d like to thank Focus Features for sponsoring this video – and for inviting us to pre-screen their summer 2015 film “Self/Less”. It’s a sci-fi flick that explores memory, consciousness, and immortality, and it made us think about the types of immortality that already exist here on Earth. A big thanks to Focus Features for supporting MinuteEarth! http://www.focusfeatures.com/selfless

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Want to learn more about the topic in this week’s video? Here are some key words/phrases to get your googling started:
– negligible senescence: not showing signs of age-related progression
– biological immortality: having a mortality rate that does not increase with increasing age

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With the MinuteEarth team: Alex Reich, Peter Reich, Emily Elert, Ever Salazar, Kate Yoshida, and Henry Reich. Music by Nathaniel Schroeder: http://www.soundcloud.com/drschroeder
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References:

Aubert, G. & Lansdorp, P. M. (2008) Telomeres and aging. Physiological Review 88(2): 557–579. http://simonadellemonache.com/dispensa%206b%20-telomerasi%20e%20cancro.pdf

Bavestrello, G. Sommer, C., and Sará, M. 1992. Bi-directional conversion in Turritopsis nutricula. In Aspects of Hydrozoan Biology. (J. Bouillon et al., editors). Scientia Marina 56 (2-3): 137-140. http://www.icm.csic.es/scimar/pdf/56/sm56n2137.pdf

Buffenstein R. (2008) Negligible senescence in the longest living rodent, the naked mole rat: Insights from a successfully aging species. Journal of Comparative Physiology B 178: 439-445. http://link.springer.com/article/10.1007%2Fs00360-007-0237-5

Finch, C.E. (1998) Variations in senescence and longevity include the possibility of negligible senescence. Journal of Gerontology: Biological Sciences 53A(4): B235–239. http://biomedgerontology.oxfordjournals.org/content/53A/4/B235.full.pdf

Piraino, S., Boero, F., Aeschbach, B., Schmid, V. (1996) Reversing the life cycle: medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa). Biological Bulletin 190: 302-312. http://www.researchgate.net/profile/Ferdinando_Boero/publication/230806599_Reversing_the_Life_Cycle_Medusae_Transforming_into_Polyps_and_Cell_Transdifferentiation_in_Turritopsis_nutricula_(Cnidaria_Hydrozoa)/links/09e415049c1ffe92d6000000.pdf

Tian, X., Azpurua, J., Hine, C., Vaidya, A., Myakishev-Rempel, M., Ablaeva, J., Mao, Z., Nevo, E., Gorbunova, V., & Seluanov, A. (2013) High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature 499: 346–349. http://www.nature.com/nature/journal/v499/n7458/full/nature12234.html
Image Credits: Nake Mole Rat - Buffenstein/Barshop Institute/UTHSCSA
https://www.flickr.com/photos/jedimentat/7557258168/

Naked Mole Rat - Roman Klementschitz, Wien
https://en.wikipedia.org/wiki/File:Nacktmull.jpg

Chipmunk - Gilles Gonthier
https://www.flickr.com/photos/gillesgonthier/8101118739

Capybara - Karoly Lorentey
https://www.flickr.com/photos/lorentey/5592629831

Видео Do We Have to Get Old and Die? канала MinuteEarth