Overview: The Most and Least Effective Antidepressants
522 randomized controlled trials involving 21 antidepressants and 116,477 people were analyzed. It appears the most effective antidepressants (at a duration of 8 weeks) include amitriptyline, escitalopram, mirtazapine, paroxetine, and venlafaxine.
While reboxetine and trazodone had notably lower efficacy ratings. Some of the most effective drugs had lower tolerability scores, however, indicating they may have a greater side effect burden.
The antidepressant literature shows signs of potential bias, so the results have to be considered with that in mind.
More detailed overview: https://thedrugclassroom.com/overview-least-effective-antidepressants/
Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/8cg969/overview_the_most_and_least_effective/
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Видео Overview: The Most and Least Effective Antidepressants канала The Drug Classroom
While reboxetine and trazodone had notably lower efficacy ratings. Some of the most effective drugs had lower tolerability scores, however, indicating they may have a greater side effect burden.
The antidepressant literature shows signs of potential bias, so the results have to be considered with that in mind.
More detailed overview: https://thedrugclassroom.com/overview-least-effective-antidepressants/
Reddit discussion: https://www.reddit.com/r/TheDrugClassroom/comments/8cg969/overview_the_most_and_least_effective/
------------
Donate to The Drug Classroom:
https://www.patreon.com/TheDrugClassroom
https://www.paypal.me/TheDrugClassroom
Bitcoin: 1HsjCYpBHKcVCaW4uKBraCGkc1LK8xoj1B
------------
Thank you to my Patreon supporters: RollSafe.org, Gui Kirsch, Jonathon Dunn, Thomas Anaya, michael hoogwater, Beau Jaco, Alexander Pavlenko, Lars Nilsson, Billy, Abdulaziz Al-Kuwari, Sam A., Reece hosford, Felix Wisniewski, Jarrod o'connell, Daniel X Moore, Dahmon Bicheno, Christoffer Finstad, Zachary Thomas Binkley, Sami Parsegov, Dane Overman, Squadra Dumay, Dragonhax, Case van der Burg, John Riccardi, Matúš Zdút, Sebastian, Jacob Fournier-Paradis, Ben Shipp, Connor Sutton, Brian Henry, Adrian Selnes, Victor Stasek, Marty Sederberg, Eli Gilli Foldbo, Robert Slowley, Kate Crilly, Chandler Ledbetter, Garrett Troutman, and David Kernell.
------------
Facebook - http://facebook.com/thedrugclassroom
Twitter - http://twitter.com/drugclassroom
Email - seth@thedrugclassroom.com
------------
The Drug Classroom (TDC) is dedicated to providing the type of drug education everyone should have. Drugs are never going to leave our society and there has never been a society free from drugs.
Therefore, it only makes sense to provide real education free from propaganda.
TDC doesn't advocate drug use. Rather, we operate with the intention of reducing the harm some substances can bring.
Feel free to ask questions!
Видео Overview: The Most and Least Effective Antidepressants канала The Drug Classroom
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