Experiment on Franz Diffusion Cell | Absorption Study

In this video, we demonstrate the Experiment on Franz Diffusion Cell – Absorption Study, an important practical in pharmaceutics used to evaluate drug permeation through membranes.

The Franz Diffusion Cell is widely used for in vitro drug release and absorption studies, especially for topical and transdermal formulations. This experiment helps in understanding how a drug diffuses across a membrane under controlled conditions.

🔬 Aim of the Experiment:

To study the absorption and diffusion of a drug using Franz Diffusion Cell.

⚙️ Principle:

The drug diffuses from the donor compartment to the receptor compartment through a semi-permeable membrane, following concentration gradient principles.

🧾 Materials Required:

Franz Diffusion Cell apparatus
Membrane (synthetic/biological)
Drug formulation (gel/cream/solution)
Phosphate buffer (receptor medium)
Magnetic stirrer
Pipette and sampling tubes

🧑‍🔬 Procedure:

Prepare and mount the membrane between donor and receptor compartments.
Fill the receptor compartment with buffer solution.

Maintain constant temperature and stirring.
Apply the drug sample in the donor compartment.

Withdraw samples at specific time intervals.
Analyze the samples using suitable analytical method.

📊 Applications:
Transdermal drug delivery studies
Drug permeation and absorption analysis
Formulation development and evaluation

🎓 Useful For:
B.Pharm, M.Pharm, and research students in pharmaceutics.

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Видео Experiment on Franz Diffusion Cell | Absorption Study канала Dr. Deepika