The Boy Who Rubbed 1 Tube Of Pain Relief Cream Between His Legs

​@chubbyemu video of this case: https://youtu.be/Le-IKCLGT9A
A Toddler Drank His Mom's Essential Oils: https://youtu.be/TZr0nt2hxbs
Audio-podcast version of this video: https://anchor.fm/chubbyemu
Interview With a DNP Accident Survivor: https://youtu.be/o15HCjtSkug

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Patient portrayed by Abram Cutshall
Mom and her toddler portrayed by Megan Pulley and her son

2-4-Dinitrophenol is also an uncoupler of oxidative phosphorylation on top of salicylate

References:
Salicylate Toxicity from Exposure to a Methylsalicylate-Containing Rubefacient. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786239/

Regional variation in percutaneous penetration of 14C cortisol in man. https://www.jidonline.org/article/S0022-202X(15)47268-9/pdf

Anatomy and physiology of chronic s pain https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503924/

Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes. https://pubmed.ncbi.nlm.nih.gov/10634967/

ISPAD Clinical Practice Consensus Guidelines 2018: DKA and the hyperglycemic hyperosmolar state. https://pubmed.ncbi.nlm.nih.gov/29900641/

Salicylates. Goldfrank, Lewis R, and Neal Flomenbaum. Goldfrank's Toxicologic Emergencies. New York: McGraw-Hill, 2006.

Unconscious Uncoupling – Managing pH in Salicylate. Tox and Hound. https://toxandhound.com/toxhound/phinasa/

Counterproductive effects of sodium bicarbonate in DKA. https://pubmed.ncbi.nlm.nih.gov/8550770/

Anti-Inflammatory Drugs in Patients with Ischemic Heart Disease. Journal of Clinical Medicine 10(13):2835

Risk Factors for Cerebral Edema in Children with Diabetic Ketoacidosis. N Engl J Med 2001; 344:264-269. Risk Factors for Cerebral Edema in Children with Diabetic Ketoacidosis

Role of the mitochondrial permeability transition in salicylate toxicity to cultured rat hepatocytes: implications for the pathogenesis of Reye's syndrome. Toxicol Appl Pharmacol . 1997 Dec;147(2):431-41. https://pubmed.ncbi.nlm.nih.gov/9439738/

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