Temozolomide — DNA Methylation That Kills Tumor Cells #pharmecy #medicine

A 35-second cinematic scientific breakdown of Temozolomide, an oral alkylating chemotherapy drug used mainly in brain tumors such as glioblastoma. The video explains its conversion into the active metabolite MTIC, which methylates DNA (especially guanine bases), causing replication errors, strand breaks, and ultimately tumor cell apoptosis. It also highlights why tumor sensitivity depends on DNA repair capacity (MGMT activity).

Видео Temozolomide — DNA Methylation That Kills Tumor Cells #pharmecy #medicine канала ClinixDose