La VERDAD sobre la IVERMECTINA y el CORONAVIRUS / COVID
Hace apenas unas semanas, la EMA, agencia europea del medicamento, se pronunciaba sobre las recomendaciones para el uso de la ivermectina en el tratamiento de la infección por coronavirus, opinión también compartida por la FDA (Agencia del medicamento en EEUU). Sus conclusiones eran que, de momento, no había datos que apoyen el uso de Ivermectina para la prevención y el tratamiento de la infección por coronavirus. Comparto con ustedes los enlaces donde pueden leerse estos comunicados, así como los estudios y ensayos en los que están basados.
COMUNICADO OFICIAL DE LA EMA (AGENCIA EUROPEA DEL MEDICAMENTO)
https://www.ema.europa.eu/en/news/ema-advises-against-use-ivermectin-prevention-treatment-covid-19-outside-randomised-clinical-trials
COMUNICADO OFICIAL DE LA FDA (AGENCIA NORTEAMERICANA DEL MEDICAMENTO)
https://www.fda.gov/consumers/articulos-en-espanol/por-que-no-debe-utilizar-ivermectina-para-tratar-o-prevenir-el-covid-19
ESTUDIOS EN LOS QUE ESTAN BASADOS ESTOS COMUNICADOS
1. Elgazzar, A., et al., Efficacy and safety of ivermectin for treatment and prophylaxis of COVID-19 pandemic. Research Square, 2020.
2. Ahmed, S., et al., A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness. Int J Infect Dis, 2021. 103: p. 214-216.
3. Alam, M.T., et al., Ivermectin as pre-exposure prophylaxis for COVID-19 among healthcare providers in a selected tertiary hospital in Dhaka – an observational study. European Journal of Medical Health and Sciences, 2020.
4. Arévalo, A.P., et al., Ivermectin reduces coronavirus infection in vivo: a mouse experimental model. Biorxiv, 2020.
5. Babalola, O.E., et al., Ivermectin shows clinical benefits in mild to moderate COVID19: a randomised controlled double-blind, dose-response study in Lagos. QJM, 2021.
6. Behera, P., et al., Prophylactic role of ivermectin in SARS-CoV-2 infection among healthcare workers. Research Square, 2021.
7. Bray, M., et al., Ivermectin and COVID-19: a report in antiviral research, widespread interest, an FDA warning, two letters to the editor and the authors' responses. Antiviral Res, 2020. 178: p. 104805.
8. Caly, L., et al., The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Res, 2020. 178: p. 104787.
9. Camprubí, D., et al., Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients. PLoS One, 2020. 15(11): p. e0242184.
10. Carvallo, H., et al., Safety and efficacy of the combined use of ivermectin, dexamethasone, enoxaparin and aspirin against COVID 19. MedRxiv, 2020.
11. Carvallo, H., et al., Study of the efficacy and safety of topical ivermectin + iota-carrageenan in the prophylaxis against COVID-19 in health personnel. Journal of Biomedical Research and Clinical Investigation, 2020.
12. Castañeda-Sabogal, A., et al., Outcomes of ivermectin in the treatment of COVID-19: a systematic review and meta-analysis. Medrxiv, 2021.
13. Chaccour, C., et al., Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats. Sci Rep, 2020. 10(1): p. 17073.
14. Chaccour, C., et al., The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: a pilot, double-blind, placebo-controlled, randomized clinical trial. EClinicalMedicine, 2021: p. 100720.
15. Chachar, A.Z.K., et al., Effectiveness of ivermectin in SARS-CoV-2/COVID-19 patients. International Journal of Sciences, 2020. 9(09): p. 31-35.
16. Chowdhury, A.T.M.M., et al., A randomized trial of ivermectin-doxycycline and hydroxychloroquine-azithromycin therapy on COVID19 patients. Research Square, 2020.
17. de Melo, G.D., et al., Anti-COVID-19 efficacy of ivermectin in the golden hamster. BioRxiv, 2020.
18. Elalfy, H., et al., Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID‐19. J Med Virol, 2021.
19. Errecalde, J., et al., Safety and pharmacokinetic assessments of a novel ivermectin nasal spray formulation in a pig model. J Pharm Sci, 2021.
20. Espitia-Hern, G., et al., Effects of ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study. Biomedical Research, 2020.
21. Formiga, F.R., et al., Ivermectin: an award-winning drug with expected antiviral activity against COVID-19. J Control Release, 2020.
22. Gonzalez, J.L.B., et al., Efficacy and safety of ivermectin and hydroxychloroquine in patients with severe COVID-19. A randomized controlled trial. Medrxiv, 2021.
23. Gorial, F.I., et al., Effectiveness of ivermectin as add-on therapy in COVID-19 management (pilot trial). Medrxiv, 2020.
... EL RESTO DE REFERENCIAS PUEDEN ENCONTRARLOS EN LA PROPIA PAGINA DE LA EMA
Видео La VERDAD sobre la IVERMECTINA y el CORONAVIRUS / COVID канала Doctor Salaberri
COMUNICADO OFICIAL DE LA EMA (AGENCIA EUROPEA DEL MEDICAMENTO)
https://www.ema.europa.eu/en/news/ema-advises-against-use-ivermectin-prevention-treatment-covid-19-outside-randomised-clinical-trials
COMUNICADO OFICIAL DE LA FDA (AGENCIA NORTEAMERICANA DEL MEDICAMENTO)
https://www.fda.gov/consumers/articulos-en-espanol/por-que-no-debe-utilizar-ivermectina-para-tratar-o-prevenir-el-covid-19
ESTUDIOS EN LOS QUE ESTAN BASADOS ESTOS COMUNICADOS
1. Elgazzar, A., et al., Efficacy and safety of ivermectin for treatment and prophylaxis of COVID-19 pandemic. Research Square, 2020.
2. Ahmed, S., et al., A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness. Int J Infect Dis, 2021. 103: p. 214-216.
3. Alam, M.T., et al., Ivermectin as pre-exposure prophylaxis for COVID-19 among healthcare providers in a selected tertiary hospital in Dhaka – an observational study. European Journal of Medical Health and Sciences, 2020.
4. Arévalo, A.P., et al., Ivermectin reduces coronavirus infection in vivo: a mouse experimental model. Biorxiv, 2020.
5. Babalola, O.E., et al., Ivermectin shows clinical benefits in mild to moderate COVID19: a randomised controlled double-blind, dose-response study in Lagos. QJM, 2021.
6. Behera, P., et al., Prophylactic role of ivermectin in SARS-CoV-2 infection among healthcare workers. Research Square, 2021.
7. Bray, M., et al., Ivermectin and COVID-19: a report in antiviral research, widespread interest, an FDA warning, two letters to the editor and the authors' responses. Antiviral Res, 2020. 178: p. 104805.
8. Caly, L., et al., The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Res, 2020. 178: p. 104787.
9. Camprubí, D., et al., Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients. PLoS One, 2020. 15(11): p. e0242184.
10. Carvallo, H., et al., Safety and efficacy of the combined use of ivermectin, dexamethasone, enoxaparin and aspirin against COVID 19. MedRxiv, 2020.
11. Carvallo, H., et al., Study of the efficacy and safety of topical ivermectin + iota-carrageenan in the prophylaxis against COVID-19 in health personnel. Journal of Biomedical Research and Clinical Investigation, 2020.
12. Castañeda-Sabogal, A., et al., Outcomes of ivermectin in the treatment of COVID-19: a systematic review and meta-analysis. Medrxiv, 2021.
13. Chaccour, C., et al., Nebulized ivermectin for COVID-19 and other respiratory diseases, a proof of concept, dose-ranging study in rats. Sci Rep, 2020. 10(1): p. 17073.
14. Chaccour, C., et al., The effect of early treatment with ivermectin on viral load, symptoms and humoral response in patients with non-severe COVID-19: a pilot, double-blind, placebo-controlled, randomized clinical trial. EClinicalMedicine, 2021: p. 100720.
15. Chachar, A.Z.K., et al., Effectiveness of ivermectin in SARS-CoV-2/COVID-19 patients. International Journal of Sciences, 2020. 9(09): p. 31-35.
16. Chowdhury, A.T.M.M., et al., A randomized trial of ivermectin-doxycycline and hydroxychloroquine-azithromycin therapy on COVID19 patients. Research Square, 2020.
17. de Melo, G.D., et al., Anti-COVID-19 efficacy of ivermectin in the golden hamster. BioRxiv, 2020.
18. Elalfy, H., et al., Effect of a combination of nitazoxanide, ribavirin, and ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID‐19. J Med Virol, 2021.
19. Errecalde, J., et al., Safety and pharmacokinetic assessments of a novel ivermectin nasal spray formulation in a pig model. J Pharm Sci, 2021.
20. Espitia-Hern, G., et al., Effects of ivermectin-azithromycin-cholecalciferol combined therapy on COVID-19 infected patients: A proof of concept study. Biomedical Research, 2020.
21. Formiga, F.R., et al., Ivermectin: an award-winning drug with expected antiviral activity against COVID-19. J Control Release, 2020.
22. Gonzalez, J.L.B., et al., Efficacy and safety of ivermectin and hydroxychloroquine in patients with severe COVID-19. A randomized controlled trial. Medrxiv, 2021.
23. Gorial, F.I., et al., Effectiveness of ivermectin as add-on therapy in COVID-19 management (pilot trial). Medrxiv, 2020.
... EL RESTO DE REFERENCIAS PUEDEN ENCONTRARLOS EN LA PROPIA PAGINA DE LA EMA
Видео La VERDAD sobre la IVERMECTINA y el CORONAVIRUS / COVID канала Doctor Salaberri
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