Truqap Survival Data & What's Next with Drs. Marcela Mazo Canola, Akshjot Puri & Giancarlo Moscol

How should clinicians interpret the overall survival findings for capivasertib, and what comes next for the PI3K/AKT pathway?

Dr. Marcela Mazo Canola, Dr. Akshjot Puri, and Dr. Giancarlo Moscol discuss the updated overall survival results from CAPItello-291 and what they mean for patients with HR-positive, HER2-negative metastatic breast cancer. The conversation explores why progression-free survival, quality of life, and delaying chemotherapy remain important treatment goals in an era increasingly shaped by antibody-drug conjugates.

The experts also examine emerging data with inavolisib and gedatolisib, including the potential for comprehensive PI3K/AKT/mTOR pathway inhibition in both mutated and wild-type tumors. They discuss how new targeted therapies may expand treatment options, preserve endocrine-based strategies, and help further personalize care.
As the treatment landscape continues to evolve, understanding how to evaluate clinical benefit beyond overall survival is becoming increasingly important for treatment sequencing and long-term patient outcomes.

Watch more expert oncology discussions from Community Health Media and subscribe for the latest advances in breast cancer care.

#CommunityHealthMedia #CHM #BreastCancer #MetastaticBreastCancer #HRPositiveBreastCancer #HER2NegativeBreastCancer #Capivasertib #Truqap #CAPItello291 #Gedatolisib #Inavolisib #PIK3CA #AKTPathway #mTOR #TargetedTherapy #PrecisionOncology #MarcelaMazoCanola #AkshjotPuri #GiancarloMoscol #BreastOncology
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Видео Truqap Survival Data & What's Next with Drs. Marcela Mazo Canola, Akshjot Puri & Giancarlo Moscol канала Community Health Media