The Immune System Part 9

The immune system can be divided into the innate immune system and the adaptive immune system.

The innate immune system is the immunological mechanisms for clearing infections which are not specific to the pathogen. The two major examples are the complement systems and phagocytosis.

In contrast the mechanisms of the adaptive immune system are specific to the pathogen. The adaptive immune system is orchestrated by the lymphocytes. Lymphocytes unlike neutrophils (the main cells of the innate immune system) are specific to the pathogen they target.

The adaptive immune response can be divided into cell-mediated and humeral components. The Humeral component involves the B cells producing antibodies specific to the pathogen which are placed into the blood and go to the site of infection to help clear it. Whilst the cell-mediated component involves T cells going to the infected tissue themselves to help clear the infection

The video is long (24 parts), so I include below a contents guide.

Part 1. This part is an introduction and we talk about the first line of defence against infection, which is the epithelial barriers.

Parts 2-8. In these seven parts we discuss the innate immune system (the second line of defence). In parts 2 and 3 we discuss the acute inflammatory response (PAMPs, DAMPs, inflammatory cytokines, vasodilation and exudate formation). In Part 4 we discuss the systemic acute phase reaction. In parts 5 and 6 we discuss the complement cascades. In part 7 we discuss leukocyte extravasation and in part 8 we discuss phagocytosis.

Parts 9-24. The remainder of the video is devoted to the adaptive immune system. Parts 9 and 10 discuss the structure and function of the Major Histocompatibility Complex (MHC) proteins Parts 11 to 13 discuss the T cell receptor (TCR) and T cell development. Parts 14 and 15 discuss antigen presentation and part 16 discusses T cell activation. Part 17 discuss cytotoxic T cell function in cell mediated immunity and part 18 discusses the different types of helper T cells and their different roles. In part 19 we move on to the B cells. Parts 19 to 21 discuss B cell development and Immunoglobulin structure and types. Parts 22 to 24 then discuss B cell activation to produce plasma cells and the production and function of antibody.

Видео The Immune System Part 9 канала Elliot Nicholson