Argireline: Botox In A Bottle | Is Argireline Safe for the Eyes? | Is Argireline Harmful?

In this video, Dr. D explains if Argireline is safe for the eyes and what it is. She talks about several resources she found to explain whether or not you should reconsider using Argireline(also called acetyl hexapeptide 8) around the eyes!

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⏱️ Timecodes:
00:00 Intro
01:55 What is Argireline?
02:41 Botox vs Argireline
3:00 Wrinkles
04:25 Pre-print Article
05:24 Should I use it?
06:24 Truth in Aging Website

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If you’re interested in improving the appearance of your periocular region with an at-home treatment, you’re not alone! Argireline is an over-the-counter product that some call “Botox in a Bottle” But does it pass the eye test for use around those precious peepers?

First, What is Argireline? Argireline is actually just the brand name for a synthetic polypeptide called acetyl hexapeptide 3 or acetyl hexapeptide-8. Peptides are short chains of amino acids, the foundation for proteins including collagen and elastin, making them essential for healthy, youthful skin. It does prevent muscle movement and also promotes collagen production, so it seems like a really great idea!

Here’s what Argirilene actually does: It acts as a competitive SNAP-25 inhibitor, inhibiting the release of acetylcholine at the neuromuscular junction and temporarily paralyzing superficial facial muscles. Compared to Botox, its potency is lower but so is its toxicity.

We must also consider the Effect on Ocular Muscles - The problem is that this neurotoxic chemical may weaken the orbicularis muscle, creating the promised wrinkle-smoothing effect but also thereby potentially working counter to our blink exercise counseling efforts.

So should I use it? Argireline may be well marketed, and you may come across versions that say they are hydrating or safe. Many do contain hyaluronic acid, and you know I typically like that moisturizer for use around the eye.

But unfortunately, I DO NOT recommend using Argireline. Dermatologists don’t tend to either, as I found in one article linked below.

📚 Research Links: https://www.byrdie.com/argireline-for-skin-477134946054.pdf (patientpop.com)

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👁️ We are Salisbury Eyecare and Eyewear – a cold start optometry practice and optical shop that is owned and operated by Dr. Melanie Denton Dombrowski in downtown Salisbury, NC. We provide medical and routine eye care and Dr. Denton specializes in dry eye treatment and management of various ocular diseases. We started this channel to provide patient education and eye-related product reviews, as well as to share our experiences in the office and at community events. None of our videos are directly sponsored. We hope you enjoy our videos! Make sure to leave comments and suggestions about what you’d like to see next!
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Видео Argireline: Botox In A Bottle | Is Argireline Safe for the Eyes? | Is Argireline Harmful? канала Eye School with Dr. D