Pandemic learning from Japan
Japan
Dynamic Change of COVID-19 Seroprevalence among Asymptomatic Population in Tokyo during the Second Wave (Tokyo and Boston)
https://www.medrxiv.org/content/10.1101/2020.09.21.20198796v1.full.pdf
Population 127 million
Cases, 89,650
Deaths, 1,631
Fatality rates, low compared to Western Countries
Decreased despite the absence of lockdown
? low infection prevalence
? low IFR
Seroprevalence among asymptomatic employees, Tokyo
May 26 to August 25
Healthy volunteer workers, n = 1,877
IgM and IgG antibodies, test repeated at a month
Symptomatics excluded
Seroconversion
Seroreversion
Results
615 healthy volunteers received at least one test
Seroprevalence increased from 5.8 % to 46.8 % over summer
Paralleling the rise in daily confirmed cases within Tokyo
Exclusion of individuals with clinical symptoms, probable underestimation
Peaked on August 4
Peaked with the peak of the second wave
Out of the 350 individuals who completed both offered tests
21.4 % who tested seronegative became seropositive
Seroreversion was found in 12.2 % of initially seropositive participants
81.1% of IgM positive cases at first testing became IgM negative in approximately one month
IgM+/IgG- was the least common, 0.4% (3/700 total tests)
Short time frame between developing IgM then developing IgG
None of the seroconverted individuals were hospitalized or died
Conclusions
COVID-19 infection may have spread widely across the general population of Tokyo
Despite the very low fatality rate
Temporal correlation between the rise in seropositivity and the decrease in reported COVID-19 cases
How to explain?
Local observations
Masks culture
Non-tactile culture
Quite culture
Ventilation culture
App use
Limited international travel
Supervised quarantine, 14 days
Diet
Why Is the Obesity Rate So Low in Japan and High in the U.S.? (Research Gate)
https://www.researchgate.net/publication/23519385_Why_Is_the_Obesity_Rate_So_Low_in_Japan_and_High_in_the_US_Some_Possible_Economic_Explanations
BMI over 30, international standard for obesity
Japan, 3.6%
US, 32.0%
BMI over 25, overweight
Japan, 24.7%
US, 66.5%
The average person in Japan consumes over 200 fewer calories per day than the average American
Drive less, walk more, use more public transport
Видео Pandemic learning from Japan канала Dr. John Campbell
Dynamic Change of COVID-19 Seroprevalence among Asymptomatic Population in Tokyo during the Second Wave (Tokyo and Boston)
https://www.medrxiv.org/content/10.1101/2020.09.21.20198796v1.full.pdf
Population 127 million
Cases, 89,650
Deaths, 1,631
Fatality rates, low compared to Western Countries
Decreased despite the absence of lockdown
? low infection prevalence
? low IFR
Seroprevalence among asymptomatic employees, Tokyo
May 26 to August 25
Healthy volunteer workers, n = 1,877
IgM and IgG antibodies, test repeated at a month
Symptomatics excluded
Seroconversion
Seroreversion
Results
615 healthy volunteers received at least one test
Seroprevalence increased from 5.8 % to 46.8 % over summer
Paralleling the rise in daily confirmed cases within Tokyo
Exclusion of individuals with clinical symptoms, probable underestimation
Peaked on August 4
Peaked with the peak of the second wave
Out of the 350 individuals who completed both offered tests
21.4 % who tested seronegative became seropositive
Seroreversion was found in 12.2 % of initially seropositive participants
81.1% of IgM positive cases at first testing became IgM negative in approximately one month
IgM+/IgG- was the least common, 0.4% (3/700 total tests)
Short time frame between developing IgM then developing IgG
None of the seroconverted individuals were hospitalized or died
Conclusions
COVID-19 infection may have spread widely across the general population of Tokyo
Despite the very low fatality rate
Temporal correlation between the rise in seropositivity and the decrease in reported COVID-19 cases
How to explain?
Local observations
Masks culture
Non-tactile culture
Quite culture
Ventilation culture
App use
Limited international travel
Supervised quarantine, 14 days
Diet
Why Is the Obesity Rate So Low in Japan and High in the U.S.? (Research Gate)
https://www.researchgate.net/publication/23519385_Why_Is_the_Obesity_Rate_So_Low_in_Japan_and_High_in_the_US_Some_Possible_Economic_Explanations
BMI over 30, international standard for obesity
Japan, 3.6%
US, 32.0%
BMI over 25, overweight
Japan, 24.7%
US, 66.5%
The average person in Japan consumes over 200 fewer calories per day than the average American
Drive less, walk more, use more public transport
Видео Pandemic learning from Japan канала Dr. John Campbell
Показать
Комментарии отсутствуют
Информация о видео
Другие видео канала
Viral survivalWeekend Pandemic UpdateArguments, Great Barrington DeclarationPresident Trump's medications in detailPandemic, Monday 12 OctoberLong term COVIDPandemic, Sunday Updates and ReflectionsPresident Trump’s Covid-19 Diagnosis: Implications for Transmission, Treatment, and PrognosisAustralia, Europe and the untreatedA new symptom and more argumentPandemic Update, Europe and USCOVID developments, UK US and CanadaPandemic Science, Vaccines soonDissenting scientists issue Covid-19 herd immunity declarationUK, German fresh air and Neanderthal genesUS Coronavirus Weekend UpdateAn Update on Covid-19 Testing, Treatments, and VaccinesThe Crisis Going On Right Now, That You Are Not Being Told About...Pandemic, mostly good newsFriday 10th April and Immunity