No, BA.5 Does NOT Cause More Severe Disease Than BA.1 or BA.2

No, BA.5 Does NOT Cause More Severe Disease

An article written in a commercial online site has presented a set of in-vitro studies to demonstrate that BA.4 and BA.5 are more severe than BA.1 and BA.2. Let's review the data.

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This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
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Page 1 for the proportion of BA.4 and BA.5 in the UK
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1086494/Technical-Briefing-43-28.06.22.pdf
https://ourworldindata.org/grapher/covid-variants-area?country=~GBR

Deaths in the US and UK are down
https://ourworldindata.org/covid-deaths
URL list from Wednesday, Jul. 6 2022

Virological characteristics of SARS-CoV-2 BA.2 variant | bioRxiv
https://www.biorxiv.org/content/10.1101/2022.02.14.480335v1

Virological characteristics of the novel SARS-CoV-2 Omicron variants including BA.2.12.1, BA.4 and BA.5 | bioRxiv
https://www.biorxiv.org/content/10.1101/2022.05.26.493539v1

Outcomes of SARS-CoV-2 Reinfection | Research Square
https://www.researchsquare.com/article/rs-1749502/v1

Omicron sub-variants may target lungs, evade vax, prior infection: Studies | Business Standard News
https://www.business-standard.com/article/current-affairs/omicron-sub-variants-may-target-lungs-evade-vax-prior-infection-studies-122062301066_1.html

Neutralization Escape by SARS-CoV-2 Omicron Subvariants BA.2.12.1, BA.4, and BA.5 | NEJM
https://www.nejm.org/doi/full/10.1056/NEJMc2206576

Implications of the emergence and spread of the SARS-CoV-2 variants of concern BA.4 and BA.5 for the EU/EEA
https://www.ecdc.europa.eu/en/news-events/implications-emergence-spread-sars-cov-2-variants-concern-ba4-and-ba5

Coronavirus (COVID-19) Deaths - Our World in Data
https://ourworldindata.org/covid-deaths

What Omicron’s BA.4 and BA.5 variants mean for the pandemic
https://www.nature.com/articles/d41586-022-01730-y

Outcomes of laboratory-confirmed SARS-CoV-2 infection during resurgence driven by Omicron lineages BA.4 and BA.5 compared with previous waves in the Western Cape Province, South Africa | medRxiv
https://www.medrxiv.org/content/10.1101/2022.06.28.22276983v2

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar
https://www.news-medical.net/news/20220630/South-African-study-shows-COVID-severity-of-Omicron-BA1-BA4-BA5-all-similar.aspx

Coronavirus (COVID-19) Cases - Our World in Data
https://ourworldindata.org/covid-cases

Coronavirus (COVID-19) Deaths - Our World in Data
https://ourworldindata.org/covid-deaths

SARS-CoV-2 variants of concern and variants under investigation
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1086494/Technical-Briefing-43-28.06.22.pdf

SARS-CoV-2 variants in analyzed sequences, United Kingdom
https://ourworldindata.org/grapher/covid-variants-area?country=~GBR

Coronavirus (COVID-19) Hospitalizations - Our World in Data
https://ourworldindata.org/covid-hospitalizations

Coronavirus (COVID-19) Deaths - Our World in Data
https://ourworldindata.org/covid-deaths

Coronavirus (COVID-19) latest insights - Office for National Statistics
https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19latestinsights/infections

United Kingdom: the latest coronavirus counts, charts and maps
https://graphics.reuters.com/world-coronavirus-tracker-and-maps/countries-and-territories/united-kingdom/

CDC COVID Data Tracker: Variant Proportions
https://covid.cdc.gov/covid-data-tracker/#variant-proportions

COVID: Is Omicron Less Severe Than Delta?
https://health-study.joinzoe.com/blog/covid-omicron-less-severe

SARS-CoV-2 Omicron variant causes mild pathology in the upper and lower respiratory tract of hamsters | Nature Communications
https://www.nature.com/articles/s41467-022-31200-y

Coronavirus (COVID-19) Deaths - Our World in Data
https://ourworldindata.org/covid-deaths

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