codon model selection CMS | adoptive selection | Datamonkey | Positive selection | Stanfel similarit

Codon models are one of the main tools used to infer selection on protein-coding genes. This is done by comparing the rate of nonsynonymous substitutions (dN) that are changing the amino acid sequence with the rate of synonymous substitutions (dS) that do not affect this amino acid sequence. Although there is overwhelming evidence of negative and positive selection acting on the amino acid sequence of the proteins, synonymous substitutions affecting the protein-coding genes are assumed to be effectively neutral in most current models.
We use the classical datamonkey online tool to do the CMS analysis of our data.
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Видео codon model selection CMS | adoptive selection | Datamonkey | Positive selection | Stanfel similarit канала Genome Wide Study