AI can analyze gut bacteria to accurately diagnose Complex Regional Pain Syndrome

A groundbreaking peer-reviewed study from McGill University demonstrates that AI can analyze gut bacteria to accurately diagnose Complex Regional Pain Syndrome (CRPS)—a chronic pain condition affecting millions worldwide. Published in Anesthesiology, researchers used machine learning on gut microbiome samples from Israel and Canada, achieving over 90% accuracy in identifying a distinctive CRPS “microbiome signature,” even in patients whose symptoms had resolved  .

Surprisingly, this microbial pattern persisted after limb amputation—suggesting gut bacteria could predispose individuals to CRPS and might offer a non-invasive, globally applicable diagnostic tool.

📖 Read the full study: https://pubmed.ncbi.nlm.nih.gov/ (search: “Altered gut microbiome composition CRPS Anesthesiology 2025”)

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