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Stereotactic body radiotherapy compared with surgery for localised prostate cancer

Dr Nicholas van As speaks to ecancer at ASCO GU 2022 about PACE-A: An international phase 3 randomised controlled trial comparing stereotactic body radiotherapy (SBRT) with surgery for localised prostate cancer.

He explains that 123 patients were randomised 1:1 between SBRT or surgery with co-primary endpoints of urinary continence (absorbent pads per day) and bowel bother (EPIC bowel subdomain score) at 2 years.

Dr van As reports that with surgery the use of pads was 46% at 2 years and with SBRT it was 4%.

PACE-A contributes the first randomised data to the comparison of SBRT with surgery in localised prostate cancer, providing PRO data relevant to informed decision making.

Compared to surgery, patients receiving SBRT had better urinary continence and sexual bother score; clinician reported GI toxicity was low but SBRT patients reported more bowel bother at 2 years: surgery patients scored 97 and patients in the SBRT arm scored 88.7.

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Видео Stereotactic body radiotherapy compared with surgery for localised prostate cancer канала ecancer
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24 февраля 2023 г. 15:25:52
00:03:26
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