NAC N-Acetylcysteine

How does N-Acetylcysteine function in our body to help against infections and oxidative stresses.

WHO list of essential medicines: safest and most effective medicine needed in health system.

Used for acetaminophen/paracetamol overdose and to loosen thick mucus.
Appears to be safe in pregnancy

How does NAC break disulfide bonds?
https://www.researchgate.net/figure/Structural-formula-of-N-acetylcysteine-NAC-A-Disulfide-bonds-in-proteins-P-can-be_fig1_299401240

It increases the levels of glutathione in paracetamol overdose.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241507/

Role of glutathione in immunity and inflammation in the lung
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048347/

Disulfide bond reduction of vWF
https://www.ncbi.nlm.nih.gov/pubmed/20946172

N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why
https://www.tandfonline.com/doi/full/10.1080/10715762.2018.1468564

NAC functions
https://www.sciencedirect.com/topics/chemistry/cysteine

Видео NAC N-Acetylcysteine канала Drbeen Medical Lectures