Hershey and Chase experiment

In the year 1952 Alfred Hershey and Martha Chase designed a wonderful experiment to prove that the DNA acts as a genetic material.

Hershey and Chase, used radiolabelled phosphate to label the phage DNA and radiolabelled sulphate to label the phage coat proein. when the bacterial cells were infected with these bacteriophage, The bacterial cells showed radioactivity due to labelled phosphate. Based on these obervation, Hershey and Chase proved that the DNA acts as a genetic material.

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