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How Gene Therapy Extended Mouse Lifespan by 24%

Discover how telomerase gene therapy increased mouse lifespan by 24% in recent studies.

📚 References
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[1] Plasminogen Activator Inhibitor 1, Cell Senescence, and Aging-Related Diseases. | Liu RM, Nakamya MF (2026)
→ Cellular senescence, including replicative senescence (RS) and stress-induced premature senescence (SIPS), is a state of the permanent arrest of cell growth, which can occur in proliferative cells and post-mitotic cells. Cellular senescence
https://pubmed.ncbi.nlm.nih.gov/41892341/

[2] The Role of Cellular Senescence in Obstructive Airway Diseases: From Mechanisms and Therapeutic Targets. | Vrouvaki A, Moustaka Christodoulou M, Hillas G et al. (2026)
→ Cellular senescence is a stress-induced type of irreversible cell cycle arrest, driven by telomere attrition, oxidative stress, DNA damage, mitochondrial dysfunction, oncogene activation, and chronic inflammation. Senescent cells remain met
https://pubmed.ncbi.nlm.nih.gov/42074187/

[3] Protective effect of taurine on skin aging caused by deficiency of B cell-specific Moloney MLV insertion site-1. | Li J, Huang M, Chen L et al. (2026)
→ Bmi-1 deficiency leads to elevated oxidative damage and premature aging, making it a suitable model for studying the mechanisms of intrinsic skin aging. Taurine is abundant in the skin and has been shown to have various health benefits. How
https://pubmed.ncbi.nlm.nih.gov/42007129/

[4] Therapeutic effects of mesenchymal stem cell-derived extracellular vesicles from different tissue sources on diminished ovarian reserve and the related mechanisms. | Li J, Gu M, Wang Y et al. (2026)
→ BACKGROUND: Patients with diminished ovarian reserve (DOR) significantly reduced success rates in assisted reproduction, making DOR a major clinical challenge in assisted reproductive technologies. Recent studies have indicated that extrace
https://pubmed.ncbi.nlm.nih.gov/42057118/
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Видео How Gene Therapy Extended Mouse Lifespan by 24% канала Aging2042
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