Dennis O’Connell, Ascend - Stable School Podcast Episode #39

Dennis O’Connell (Co-Founder & CTO, Peregrine Limited; President, ERC-3643 Association) discusses building permissioned vault infrastructure that connects regulated real-world assets to DeFi liquidity, recorded at Stable Summit x Cannes 2026. Topics include the ERC-3643 token standard as the compliance layer for institutional tokenization, how Ascend’s permissioned vault architecture allows ERC-3643 tokens to serve as collateral on a regulated side while keeping downstream lenders and DeFi protocols permissionless, the growing adoption of ERC-3643 across banks, asset managers, and tokenization platforms, why compliance automation at the transfer level is the prerequisite for institutional DeFi participation, the role of stablecoins as collateral and settlement currency in on-chain credit markets, and the path toward interoperable tokenized asset infrastructure across chains and jurisdictions.

Chapters
00:00:00 Introduction and guest welcome at Stable Summit x Cannes 2026.
00:00:30 What Ascend is and Dennis O’Connell’s background at Peregrine and ERC-3643.
00:02:00 The ERC-3643 standard: how compliance is enforced automatically at every transfer.
00:05:00 Why institutional tokenization requires on-chain identity and permissioning rather than offchain controls.
00:08:00 Ascend’s permissioned vault model: regulated RWA collateral on one side, permissionless DeFi on the other.
00:12:00 How Ascend unlocks DeFi liquidity for institutional tokenized assets without compromising compliance.
00:16:00 Stablecoins as the settlement and collateral currency in on-chain credit markets.
00:20:00 Growing ERC-3643 adoption: banks, asset managers, and over 140 institutional deployments.
00:24:00 Interoperability across chains and the risk of fragmentation in tokenization standards.
00:28:00 Regulation as infrastructure: how MiCA and GENIUS Act create the compliance floor for institutional DeFi.
00:34:00 The three-to-five year roadmap for permissioned DeFi and regulated on-chain capital markets.
00:40:00 What success looks like for Ascend and ERC-3643 by 2028.

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Follow

➛ Dennis O’Connell on X: https://x.com/RealDennisO
➛ Dennis O’Connell on LinkedIn: https://linkedin.com/in/dennis-o-connell-3505292a
➛ Ascend on X: https://x.com/AscendFi
➛ ERC-3643 Association: https://erc3643.org

Follow Stable School
➛ Raza Zaidi (Host) on X: https://x.com/razacodes
➛ Stable Summit on X: https://x.com/stable_summit
➛ Stable School Website: https://stableschool.org/
➛ Stable School Podcast: https://www.youtube.com/@StableSchool

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About Stable School
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DISCLAIMER
The info contained herein is for informational purposes only. Nothing herein shall be construed to be financial, legal, or tax advice. The content of this video is solely the opinions of the speakers who are not a licensed financial advisor or registered investment advisor. Trading cryptocurrencies poses considerable risk of loss. The speakers do not guarantee any particular outcome.

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