Modeling 10,000 neurons

Scientists at the Allen Institute for Brain Science create models of neurons in the visual cortex of the mouse in order to better understand—and make predictions about—how neurons relay and code visual information.

This movie shows preliminary data of 10,000 neurons: 8,000 replicated pyramidal cells (an excitatory neuron, shown first) and 2,000 replicated interneurons (an inhibitory neuron, shown second). Copies of these two cells are displayed one after another in the movie until approximately 10% of the whole model is shown; more than that would be too cluttered to see what is happening. Toward the middle of the movie, the cells are colored according to their properties: excitatory in red and inhibitory in blue. The second half of the movie illustrates activity of the cells in a two second-long simulation. The cells that fire action potentials are intermittently highlighted, giving the viewer an impression of the simulated neuronal activity.

Movie and visualization software: David Feng
Model and simulation: Anton Arkhipov
Raw and processed experimental data: Staci Sorensen, Zhi Zhou, Hanchuan Peng, Aaron Oldre, Jim Berg, Shiella Caldejon, Nick Dee, Zhi Zhou, Hanchuan Peng, Michael Fisher, Alex Henry, Kevin Joines, David Sandman and Tsega Desta

Видео Modeling 10,000 neurons канала Allen Institute