Gene Editing Inside the Body Using CRISPR
CRISPR-Cas9 technology is used to edit DNA to correct genetic abnormalities, but until now has required cells be removed for gene editing outside the body. In March 2020 researchers announced a test of the first in-the-body (in vivo) CRISPR-Cas9 treatment for Leber congenital amaurosis (LCA) type 10, a condition that causes severe, early-onset vision loss. This video explains the principles of DNA editing with #CRISPR-Cas9 and the rationale for its use and testing as a therapy for LCA10 in the BRILLIANCE clinical trial. Click https://ja.ma/35adPDf to read a #JAMAMedNews review of the range of clinical trials testing CRISPR as a treatment for genetic blindness and other human diseases in 2020.
Видео Gene Editing Inside the Body Using CRISPR канала JAMA Network
Видео Gene Editing Inside the Body Using CRISPR канала JAMA Network
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