Powder XRD Revolutionizing Pharmaceutical Drug Analysis 1

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Discover how powder XRD is crucial in pharmaceutical R&D, crystal form investigation, and quality control of API powders and formulations. Learn about Rigaku's solutions for the drug manufacturing process.
[00:00-00:42]
welcome again to Pharmalytical Summit. Today, I'm gonna talk about powder XRD for pharmaceutical. I would like to acknowledge Dr. Maciej Gajzyk, my Rigaku Europe colleague. Um, the outline of my talk today is R&D processes of pharmaceutical drugs, investigation of crystal forms, quality check of API powder formulation, Rigaku solution, uh, uh, for pharmaceutical, and the summary. Let me also bring up the laser pointer. So in my view, uh, I'm not a specialist in drug design, but these are 4 major, uh, processes in the drug formulation of, uh, in the process of m- manufacturing of the drugs.
[00:42-00:59]
Physical and chemical approach, pre-formulation, investigational drug formulation/design, and the products, including the scale-up. The powder diffraction, uh, is involved in each of these steps, and hopefully in my today's talk, I will try to show you that.
[00:59-01:34]
Um, structure analysis of the target protein and API, which is in, which is in- included in the investigation of the compound. How many forms are there? The polycrystalline forms or the API. Which is the best form of the drug, which is included in the investigation of the crystal forms. And then quality check of API powder, check of quality eye- quality of API. The formulation, which is determination of the best freeze-drying process or the best tableting process. In simple form, again, what can XRD do for drug analysis?
[01:35-01:40]
X-ray diffractometers are used for pharmaceutical raw materials, formulation, R&D, and quality control.

Видео Powder XRD Revolutionizing Pharmaceutical Drug Analysis 1 канала Rigaku Corporation