Infectious Diseases & Hematology | Medicine | MBBS 4th Year | Farre Series | Dr. Santhosh Sir

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Farre annotated pdf notes: https://t.me/pwmeded/7553
In this high-yield General Medicine lecture, Dr. Santhosh Sir covers the critical topics of Infectious Diseases and Hematology for MBBS 4th Year and NEET PG 2026. This session focuses on the rapid revision of HIV/AIDS, Dengue, and Hematological Malignancies (Leukemia - AML/CML). The lecture breaks down the natural history of HIV, opportunistic infections, IRIS, and Dengue management protocols (DHF/DSS) into concise "Farre" notes. Dr. Santhosh also explains the classification and management of Acute and Chronic Myeloid Leukemias, making this essential for university theory exams and practicals.

Topics Covered:
- HIV/AIDS: Transmission, Natural History, and Opportunistic Infections (TB, PCP, Cryptococcal)
- Management of HIV: ART Regimen (TLD), IRIS Pathophysiology & Management
- Dengue Fever: Phases (Febrile, Critical, Recovery), Warning Signs, and Management (Fluids/Platelets)
- Dengue Hemorrhagic Fever (DHF) & Shock Syndrome (DSS)
- Hematological Malignancies: Classification (Leukemia vs Lymphoma)
- Acute Myeloid Leukemia (AML): Auer Rods, Gum Hypertrophy, Tumor Lysis Syndrome, & 7+3 Regimen
- Chronic Myeloid Leukemia (CML): Philadelphia Chromosome (BCR-ABL), Phases, and Tyrosine Kinase Inhibitors (Imatinib)

00:00 - Intro & Overview
03:00 - HIV: Transmission & Acute Retroviral Syndrome
08:08 - Chronic Phase & AIDS Definition
11:58 - Systemic Manifestations (Cardiomyopathy, HIVAN)
17:08 - Opportunistic Infections vs CD4 Count
22:15 - Antiretroviral Therapy (TLD Regimen)
24:50 - Immune Reconstitution Inflammatory Syndrome (IRIS)
32:48 - Dengue: Serotypes & Transmission
34:30 - Phases of Dengue (Febrile, Critical, Recovery)
46:18 - Dengue Hemorrhagic Fever & Shock Syndrome (DSS)
53:50 - Management of Dengue (Fluids & Platelets)
59:15 - Hematological Malignancies Overview
1:05:08 - Acute Myeloid Leukemia (AML): Clinical Features
1:10:50 - Diagnosis (Auer Rods) & Treatment (Induction/Consolidation)
1:18:40 - Chronic Myeloid Leukemia (CML): Pathogenesis (Philadelphia Chromosome)
1:23:05 - Phases of CML (Chronic, Accelerated, Blast Crisis)
1:31:25 - Management of CML (TKI - Imatinib)
#PWMedEd #MBBS #Medicine #InfectiousDiseases #Hematology #Malaria #Anemia #Leukemia #MBBS4thYear #NEETPG #DrSanthoshSir

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