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Bio-Inorganic Ques Solved Part-2 ||CSIR NET PYQ From 2017 to 2023

Welcome to Part 2 of CSIR NET PYQ Solving Series – Bioinorganic Chemistry Edition!
In this video, I’m solving 29 previous year questions from Bioinorganic Chemistry, carefully selected to help you master important concepts and question patterns asked in CSIR NET,GATE,SSB LECTURER,IIT JAM, CUET, PGT and other competitive exams.

Topics covered in this video:

1. Metalloproteins and Active Sites

Hemerythrin, Hemocyanin, Myoglobin, Hemoglobin (structure, oxidation states, O₂ binding)

Cytochrome P450 (mechanism, oxidation states, catalytic cycle)

Superoxide Dismutase (Cu-Zn enzyme)

Nitrogenase (ATP consumption, metal centers)

Cytochrome c oxidase (metal centers, electron and O₂ interaction)

Carboxypeptidase A (Zn²⁺ coordination and role)

Rubredoxin and Ferredoxins ([Fe-S] clusters, ligands, geometry)

2. Iron-Sulfur Clusters

Cubane-type ferredoxins (number of sulfides, ligands)

3Fe and 4Fe ferredoxins

[2Fe–2S], [4Fe–4S] clusters – structure, ligation, function

3. Metal Ions in Enzymes

Zn²⁺ (in carbonic anhydrase, carboxypeptidase, SOD)

Cu²⁺ (in blue copper proteins, nitrite reductase, hemocyanin)

Fe in cytochromes, myoglobin

Mo in nitrogenase

Metal replacement effects (Zn by Co in enzymes, etc.)

4. Ligand Interactions and Coordination Geometry

Histidine, cysteine, glutamate as protein ligands

Coordination geometry (tetrahedral, square planar, 5-coordinate, etc.)

Trans effect in cisplatin synthesis

5. Catalytic Cycles and Mechanisms

Cytochrome P450 (mechanism of O–O bond cleavage)

Oxygen evolving complex in photosynthesis

Electron transfer pathways involving heme and metal centers

6. Spectroscopic Features

EPR, UV-vis, Raman data interpretation

Blue copper proteins: absorption at ~600 nm

Hemocyanin: resonance Raman O–O stretch shift on isotope substitution

7. Medicinal Chemistry and Drug Mechanisms

Cisplatin (structure, synthesis, DNA binding)

Drug-protein interactions (Cortisone, Sulfadiazine, etc.)

Siderophores and metal ion transport (especially Fe³⁺)

Видео Bio-Inorganic Ques Solved Part-2 ||CSIR NET PYQ From 2017 to 2023 канала CHEMOPHILIC ZONE
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