DNA graffiti: mutation patterns in cancer | The Royal Society
human cancers are highly individual. Etched into the DNA of cancers are graffiti-like mutation patterns, which could reveal underlying biological abnormalities, unique to each person’s cancer, with potential for application in precision medicine.
In this lecture, Professor Serena Nik-Zainal will describe how her team have explored the extraordinary DNA graffiti that has been seen in human cancers, using a combination of big data computational approaches and systematic experimental methods. She will provide an account of how they have designed algorithms that could be used to interpret cancer genomes for clinical purposes and how they have taken steps towards clinical validation studies for her algorithms. Professor Nik-Zainal will touch on her team’s recent endeavour, reporting the largest cohort of WGS cancers worldwide of nearly 20,000 patients recruited via the NHS. She will end by bringing the audience through a selection of real cancer WGS patient stories
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Видео DNA graffiti: mutation patterns in cancer | The Royal Society канала The Royal Society
In this lecture, Professor Serena Nik-Zainal will describe how her team have explored the extraordinary DNA graffiti that has been seen in human cancers, using a combination of big data computational approaches and systematic experimental methods. She will provide an account of how they have designed algorithms that could be used to interpret cancer genomes for clinical purposes and how they have taken steps towards clinical validation studies for her algorithms. Professor Nik-Zainal will touch on her team’s recent endeavour, reporting the largest cohort of WGS cancers worldwide of nearly 20,000 patients recruited via the NHS. She will end by bringing the audience through a selection of real cancer WGS patient stories
StreamText offers a full page of captions and you can personalise the display adjusting the font, the font size and background. You can also open the link in a separate webpage, adjust the size of the page and place it at the top/bottom of the screen on which you are viewing the event if you would like to view the event and captions on one page. It needs to be opened/copied into a web browser on a phone, tablet or laptop. https://www.streamtext.net/player?event=RoyalSociety
The Royal Society is a Fellowship of many of the world's most eminent scientists and is the oldest scientific academy in continuous existence.
▶https://royalsociety.org/
🔔Subscribe to our channel for exciting science videos and live events, many hosted by Brian Cox, our Professor for Public Engagement: https://bit.ly/3fQIFXB
We’re also on Twitter ▶ https://twitter.com/royalsociety
Facebook ▶ https://www.facebook.com/theroyalsociety/
Instagram ▶ https://www.instagram.com/theroyalsociety/
And LinkedIn ▶ https://www.linkedin.com/company/the-royal-society
Видео DNA graffiti: mutation patterns in cancer | The Royal Society канала The Royal Society
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