GWAS mechanism - Lecture 13 - Deep Learning in Life Sciences (Spring 2021)

MIT 6.874/6.802/20.390/20.490/HST.506 Spring 2021 Prof. Manolis Kellis
Deep Learning in the Life Sciences / Computational Systems Biology
Playlist: https://youtube.com/playlist?list=PLypiXJdtIca5sxV7aE3-PS9fYX3vUdIOX
Latest slides and course today: http://compbio.mit.edu/6874
Spring 2021 slides and materials: http://mit6874.github.io/

00:00 Overview
01:40 GWAS review
04:00 Global enrichment analyses
14:27 Using enrichment as an empirical prior
19:30 EpiMap
24:34 Predicting sub-threshold loci
28:53 Intermediate molecular phenotypes
41:07 eQTL studies
45:53 Allelic analysis
52:21 Introduction to causality
53:50 What is causal inference
56:05 Causal effect inference using a graphical model
1:12:07 Causal effect inference in potential outcome framework
1:25:54 Causal structural inference

Видео GWAS mechanism - Lecture 13 - Deep Learning in Life Sciences (Spring 2021) канала Manolis Kellis