Does the epigenetic clock play a causal role in aging? | Steve Horvath

Although epigenetic clocks clearly *relate* to causal aspects of aging, scientists don't know if the clocks are inherently causal. At this time, the clocks are not validated for use as clinical biomarkers for individual use, but rather to look at trends across larger studies. The methylation patterns appear with age occur in polycomb group protein target regions that play a role in regulating stem cells. In this clip, Dr. Steve Horvath discusses whether epigenetic clocks play causal roles in aging.

Watch the full interview here:
https://www.youtube.com/watch?v=A_aaBKubJnA

Original episode posted December 22nd, 2020.
#GrimAge #aging #biomarker

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It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

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