Part 4 : Tissue Level of Organization | Glandular Epithelium (Hindi) | B. Pharm | Nursing

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Glandular Epithelium
A gland is one or more cells that produce and secrete a specific product. The product is always a water-based fluid (aqueous) and usually contains proteins (the product is referred to as a secretion). Secretion is considered an active process. Glandular cells obtain substances needed from blood and transform them (chemically) into a product that’s discharged from the cell.
Glands are classified into two groups based on characteristics:
1. Where they release their product- glands can be endocrine (secrete internally) or exocrine (secrete externally).
2. The number of cells they contain- glands can be unicellular (one-celled) or multicellular (more than one cell).
Endocrine Glands
Endocrine glands are also called ductless glands because eventually, they lose their ducts. They produce hormones (chemical messengers ) and secrete them by exocytosis into the extracellular space. After entering the extracellular space, they enter the blood or lymphatic fluid and travel to specific organs. Each hormone makes its target organ respond in a specific way. For instance, hormones produced by intestinal cells cause the pancreas to release enzymes that aid in digestion.
Not all endocrine glands have the the same structure, so a single description cannot be used. Typically, they are compact multicellular organs but there are individual hormone producing cells as well (specifically in digestive tract mucosa and the brain). Hormones secreted by endocrine glands vary. For instance, one gland might secrete an amino acid while another secretes glycoproteins or steroids. Important– not all endocrine glands are epithelium.
Exocrine Glands
Exocrine glands secrete their products onto the skin or into body cavities. Unicellular exocrine glands do this directly by exocytosis, while multicellular glands transport their product through a duct on the epithelial surface. Products secreted by exocrine glands include sweat, oil, mucous, bile, and more.
Unicellular exocrine glands
Important examples of unicellular glands include goblet cells (looks like a goblet) and mucous cells. Unicellular glands can be found within the epithelial linings of the intestinal and respiratory tracts.
In humans, unicellular exocrine glands produce mucin, a complex glycoprotein that dissolves in water. When the mucin is dissolved, it forms mucous (which protects and lubricates surfaces).
Multicellular exocrine glands
Structurally, multicellular exocrine glands are more complex than their unicellular neighbors. They have two main parts: an epithelium-derived duct and a secretory unit (made of secretory cells). In almost all cases, the secretory unit is surroundedby connective tissue. The connective tissue supplies the secretory unit with blood vessels and nerve fibers . It also forms a fibrous capsule that extends into the gland and divides it into lobes. Multicellular exocrine glands are classified by structure and secretion (type).
Structural classification
Multicellular exocrine glands are structurally classified depending on the structure of their duct.
• Simple glands– have an unbranched duct
• Compound glands– have a branched duct
The glands can be further categorized by their secretory units as:
• Tubular– if the secretory cells form tubes
• Alveolar– if the secretory cells form small sacs
• Tubuloalveolar– if they have both tubular and alveolar secretory units

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