How Semaglutide Promotes Weight Loss: Metabolism, Lipolysis, and Cellular Energy in 3D

Overweight and obesity represent major global medical challenges, profoundly affecting metabolic homeostasis. As adipose tissue accumulates, both anabolic and catabolic metabolic pathways become dysregulated, altering energy balance at the cellular and systemic levels.

In this video, you’ll learn how the GLP-1 receptor agonist semaglutide creates a sustained energy deficit by reducing appetite and blood glucose, triggering cellular adaptive changes (including Golgi, nuclear, ER and mitochondrial damage), activating adipocyte lipolysis to break down triglycerides into fatty acids, and how these fatty acids undergo metabolic reactions to form acetyl-CoA that enters the Krebs cycle—ultimately driving the body to use stored fat for gradual, sustained weight loss.

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Видео How Semaglutide Promotes Weight Loss: Metabolism, Lipolysis, and Cellular Energy in 3D канала VOKA 3D Anatomy & Pathology