Beautiful reconstruction of a mouse dopamine neuron.

The video shows sparse-labelling of a single dopaminergic neuron with a fluorescent protein, in a mouse brain hemisphere, that has been cleared of fat to become translucent. A z-stack of lightsheet imaging reconstructs the entire cell from its soma in the midbrain, via a single axon, to its dopaminergic terminal field in the striatum (~450,000 terminals). Work made possible by a Fixel Chair in Parkinson’s disease to Dr. Matt Farrer

Видео Beautiful reconstruction of a mouse dopamine neuron. канала Benjamin Stecher