Decoding the Cause... Why Do We Get Sick?

How does modern science arrive at conclusions on the causes of chronic diseases like atherosclerosis? How confident are we in these conclusions? And what is the difference in causation between infectious diseases and chronic conditions?

We combine positive evidence from observational trials, biochemical and tissue histology, randomized clinical drug trials and mendelian randomization genetic trials, then we come to a conclusion with high degree of certainty that a substance X is a cause for the disease Y.

00:36 Infections versus non-communicable diseases
00:59 What is a cause?
01:41 What is a risk factor ?
02:09 When does a risk factor become a cause?
02:52 Epidemiology
03:26 Association versus causation
04:17 Biochemistry & pathology
04:57 Human clinical trials
05:38 Randomization
07:06 Mendelian Randomization
09:54 Summary

Видео Decoding the Cause... Why Do We Get Sick? канала Cardio Buzz