Fecal Transplants: Paving the Future for Crohn’s Disease
This video looks at role of the bacteria and other microbes living within the human gut, referred to as the gut microbiome. It also explores how understanding more about them could hold the key to developing new treatment options for individuals with Gastrointestinal diseases such as Crohn’s Disease. These individuals often have an altered composition of their gut bacteria. In this video, we talk about a new therapy called Fecal Microbiome Transplants that aims to restore the composition to resemble a healthy microbiome.
This series was created by collaborative efforts of the McMaster students Sara Araz, Jaskaran Benepal, Alyssa Ciampa, and Aarchie Soni within the McMaster Demystifying Medicine Program.
We would like to thank Dr. Nikhil Pai for his valuable contributions to this video and his expert inputs.
Please note these videos are not meant to act as medical information or instruction and are solely for educational purposes. Please consult your health care provider for information about your health.
Copyright McMaster 2023.
#Gutmicrobiome #Crohns #scienceeducation #Fecalmicrobiometransplant #DemystifyingMedicine
References
Bojanova, D. P., & Bordenstein, S. R. (2016). Fecal Transplants: What Is Being Transferred? PLOS Biology, 14(7), e1002503. https://doi.org/10.1371/journal.pbio.1002503
Boston, 677 Huntington Avenue. (2017, August 16). The Microbiome. The Nutrition Source. https://www.hsph.harvard.edu/nutritionsource/microbiome/
Gupta, S., Allen-Vercoe, E., & Petrof, E. O. (2016). Fecal microbiota transplantation: in perspective. Therapeutic Advances in Gastroenterology, 9(2), 229–239. https://doi.org/10.1177/1756283X15607414
Kaakoush, N. O. (2020). Fecal transplants as a microbiome-based therapeutic. Current Opinion in Microbiology, 56, 16–23. https://doi.org/10.1016/j.mib.2020.05.008
Mayo Clinic Staff. (2022, August 6). Crohn’s disease - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304
Rinninella, E., Raoul, P., Cintoni, M., Franceschi, F., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C. (2019). What is the Healthy Gut Microbiota
Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases. Microorganisms, 7(1), 14. https://doi.org/10.3390/microorganisms7010014
Robertson, R. (2017, June 27). Why the Gut Microbiome Is Crucial for Your Health. Healthline. https://www.healthline.com/nutrition/gut-microbiome-and-health
Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015). Impacts of Gut Bacteria on Human Health and Diseases. International Journal of Molecular Sciences, 16(4), 7493–7519. https://doi.org/10.3390/ijms16047493
Видео Fecal Transplants: Paving the Future for Crohn’s Disease канала Demystifying Medicine McMaster
This series was created by collaborative efforts of the McMaster students Sara Araz, Jaskaran Benepal, Alyssa Ciampa, and Aarchie Soni within the McMaster Demystifying Medicine Program.
We would like to thank Dr. Nikhil Pai for his valuable contributions to this video and his expert inputs.
Please note these videos are not meant to act as medical information or instruction and are solely for educational purposes. Please consult your health care provider for information about your health.
Copyright McMaster 2023.
#Gutmicrobiome #Crohns #scienceeducation #Fecalmicrobiometransplant #DemystifyingMedicine
References
Bojanova, D. P., & Bordenstein, S. R. (2016). Fecal Transplants: What Is Being Transferred? PLOS Biology, 14(7), e1002503. https://doi.org/10.1371/journal.pbio.1002503
Boston, 677 Huntington Avenue. (2017, August 16). The Microbiome. The Nutrition Source. https://www.hsph.harvard.edu/nutritionsource/microbiome/
Gupta, S., Allen-Vercoe, E., & Petrof, E. O. (2016). Fecal microbiota transplantation: in perspective. Therapeutic Advances in Gastroenterology, 9(2), 229–239. https://doi.org/10.1177/1756283X15607414
Kaakoush, N. O. (2020). Fecal transplants as a microbiome-based therapeutic. Current Opinion in Microbiology, 56, 16–23. https://doi.org/10.1016/j.mib.2020.05.008
Mayo Clinic Staff. (2022, August 6). Crohn’s disease - Symptoms and causes. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304
Rinninella, E., Raoul, P., Cintoni, M., Franceschi, F., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C. (2019). What is the Healthy Gut Microbiota
Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases. Microorganisms, 7(1), 14. https://doi.org/10.3390/microorganisms7010014
Robertson, R. (2017, June 27). Why the Gut Microbiome Is Crucial for Your Health. Healthline. https://www.healthline.com/nutrition/gut-microbiome-and-health
Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015). Impacts of Gut Bacteria on Human Health and Diseases. International Journal of Molecular Sciences, 16(4), 7493–7519. https://doi.org/10.3390/ijms16047493
Видео Fecal Transplants: Paving the Future for Crohn’s Disease канала Demystifying Medicine McMaster
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9 февраля 2023 г. 20:00:11
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