How Vitamin D Lowers Mortality Rates Of Infections, Including COVID-19 (by Abazar Habibinia, MD):

How Vitamin D Lowers Mortality Rates Of Infections, Including COVID-19:

Part 1:
The impact of vitamin D on hospitalization and mortality rates from COVID-19.

Part 2:
The benefits you could achieve by increasing vitamin D levels to 125 nmol/L (50 ng/ml).

Part 3:
How vitamin D affects the immune system to lower mortality rates of infections, including COVID-19.

References:
Books:
1) Vitamin D: Physiology, Molecular Biology, and Clinical Applications, 2nd edition, Michael F. Holick.
2) Vitamin D, 4th edition, David Feldman, et al.

Articles:
1) The vitamin D–antimicrobial peptide pathway and its role in protection against infection
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821804/#R129

2) Suppression of Iron-Regulatory Hepcidin by Vitamin D
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3935584/

3) High-dose vitamin D3 reduces circulating hepcidin concentrations: A pilot, randomized, double-blind, placebo-controlled trial in healthy adults
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191989/

4) Immunologic Effects of Vitamin D on Human Health and Disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400911/

5) The Anti-Inflammatory Effects of Vitamin D in Tumorigenesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164284/

6) Down-regulation of IL-8 by high-dose vitamin D is specific to hyperinflammatory macrophages and involves mechanisms beyond up-regulation of DUSP1
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594277/

7) Vitamin D and inflammatory diseases
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070857/

Genes, Vitamin D and COVID-19:

1) Five key genes linked to severe COVID-19 found, suggesting drug targets
https://ca.news.yahoo.com/five-key-severe-covid-19-161436410.html

2) Genetic mechanisms of critical illness in Covid-19
https://www.nature.com/articles/s41586-020-03065-y

3) The Non-Genomic Actions of Vitamin D
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808864/

4) Differential immunomodulatory effect of vitamin D (1,25 (OH)2 D3) on the innate immune response in different types of cells infected in vitro with infectious bursal disease virus
https://www.sciencedirect.com/science/article/pii/S003257912030331X

5) Dipeptidyl peptidase 9 (DPP9) in human skin cells
https://pubmed.ncbi.nlm.nih.gov/27682012/

6) Correction of vitamin D deficiency facilitated suppression of IP-10 and DPP IV levels in patients with chronic hepatitis C: A randomised double-blinded, placebo-control trial
https://pubmed.ncbi.nlm.nih.gov/28376103/

7) Interferon alpha gene expression and serum level association with low vitamin D levels in Egyptian female patients with systemic lupus erythematosus
https://pubmed.ncbi.nlm.nih.gov/28659049/

Vitamin D and COVID-19 Death:

1) Vitamin D Insufficiency May Account for Almost Nine of Ten COVID-19 Deaths: Time to Act. Comment on: “Vitamin D Deficiency and Outcome of COVID-19 Patients”
https://www.mdpi.com/2072-6643/12/12/3642/htm

2) Vitamin D Deficiency in COVID-19 Quadrupled Death Rate
https://www.medscape.com/viewarticle/942497?fbclid=IwAR0NWyuNCW_jejztc9pkIR8WeYE1toq5fjVL65_90MUDw8ozdanrbkJQnS8

Vitamin D and COVID-19 Hospitalization:

1) More than 80 percent of hospitalized COVID-19 patients had vitamin D deficiency: study
https://www.ctvnews.ca/mobile/health/more-than-80-per-cent-of-hospitalized-covid-19-patients-had-vitamin-d-deficiency-study-1.5162396?fbclid=IwAR0MX0YidHhqSMNVmpmAKDw2v_IWq-upX6SXbDSXr6jqHMWs_qzI-4-zCqQ

2) Vitamin D Status in Hospitalized Patients with SARS-CoV-2 Infection
https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgaa733/5934827

Follow us on:
YouTube: https://www.youtube.com/c/CanadianAcademyofSportsNutrition
Facebook: https://www.facebook.com/canadianacademyofsportsnutrition/
Instagram: https://www.instagram.com/caasn2012/
Twitter: https://twitter.com/caasn2015?lang=en

Disclaimer:
For disclaimer about this video, please refer to the following link:
https://www.caasn.com/disclaimer.html

Видео How Vitamin D Lowers Mortality Rates Of Infections, Including COVID-19 (by Abazar Habibinia, MD): канала Canadian Academy of Sports Nutrition