Coronavirus, Longer term issues
Sequelae
https://www.medpagetoday.com/infectiousdisease/covid19/86482
https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf
https://covid19.joinzoe.com/post/covid-long-term
One in ten are sick for three weeks or more
COVID-19, short term illness caused by SARS-CoV-2
Most health sources, people will recover within two weeks
Some people report symptoms from 3 weeks to months
https://www.ecdc.europa.eu/en/covid-19/latest-evidence
Trigger diabetes?
https://www.nature.com/articles/d41586-020-01891-8?utm_source=Nature+Briefing&utm_campaign=a7809b0221-briefing-dy-20200624&utm_medium=email&utm_term=0_c9dfd39373-a7809b0221-44762053
Several anecdotal reports of spontaneous diabetes mellitus type 1 after COVID infection
Evidence of beta cell damage in vitro and small animal studies
Direct or indirect damage
Insulin lack
Weight loss, thirst, polyuria
Tiredness, blurred vision, local infections, ketosis
Pulmonary fibrosis
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30225-3/fulltext
Symptoms associated with acute COVID-19, mild upper respiratory tract symptoms to severe acute respiratory distress syndrome
Data from SARS and MERS
Emerging data from the COVID-19 pandemic
Could be substantial fibrotic consequences following SARS-CoV-2 infection
Idiopathic pulmonary fibrosis
Antifibrotic therapies, possible role in treatment
Might have a role in preventing fibrosis after SARS-CoV-2 infection.
Neurology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227537/
Around a third of ITU patients admitted for respiratory difficulties exhibit neurologic symptoms
? hypoxia
? inflammation
? SARS-CoV-2 dissemination into brain parenchyma
CoV infection can potentially lead to chronic neuroinflammation and progressive demyelination
Sensorimotor dysfunctions
Psychiatric disorders
Brain cell degeneration and demyelination
Видео Coronavirus, Longer term issues канала Dr. John Campbell
https://www.medpagetoday.com/infectiousdisease/covid19/86482
https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf
https://covid19.joinzoe.com/post/covid-long-term
One in ten are sick for three weeks or more
COVID-19, short term illness caused by SARS-CoV-2
Most health sources, people will recover within two weeks
Some people report symptoms from 3 weeks to months
https://www.ecdc.europa.eu/en/covid-19/latest-evidence
Trigger diabetes?
https://www.nature.com/articles/d41586-020-01891-8?utm_source=Nature+Briefing&utm_campaign=a7809b0221-briefing-dy-20200624&utm_medium=email&utm_term=0_c9dfd39373-a7809b0221-44762053
Several anecdotal reports of spontaneous diabetes mellitus type 1 after COVID infection
Evidence of beta cell damage in vitro and small animal studies
Direct or indirect damage
Insulin lack
Weight loss, thirst, polyuria
Tiredness, blurred vision, local infections, ketosis
Pulmonary fibrosis
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30225-3/fulltext
Symptoms associated with acute COVID-19, mild upper respiratory tract symptoms to severe acute respiratory distress syndrome
Data from SARS and MERS
Emerging data from the COVID-19 pandemic
Could be substantial fibrotic consequences following SARS-CoV-2 infection
Idiopathic pulmonary fibrosis
Antifibrotic therapies, possible role in treatment
Might have a role in preventing fibrosis after SARS-CoV-2 infection.
Neurology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7227537/
Around a third of ITU patients admitted for respiratory difficulties exhibit neurologic symptoms
? hypoxia
? inflammation
? SARS-CoV-2 dissemination into brain parenchyma
CoV infection can potentially lead to chronic neuroinflammation and progressive demyelination
Sensorimotor dysfunctions
Psychiatric disorders
Brain cell degeneration and demyelination
Видео Coronavirus, Longer term issues канала Dr. John Campbell
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