Cell Cycle Regulation | Basics Explained | Hindi

In this video tutorial we talk about some basic points of cell cycle regulation in Hindi.
The cells cycle can be divided into two major phases interphase and mitosis (M). During interphase the cell double its mass and duplicate its content, and spend most of the time in this phase. Mitosis is where cell division take place.

During each stage of the cell cycle, there are specific proteins or enzyme involved in its regulation. Usually they are cyclin that are involved in the cell cycle progression. This is because their concentration has been found to increase and decrease rapidly during cell cycle. In animal cells there are various cyclin and CDKs activated at different stages of cell cycle. They include, cyclin A, B, D, E and there is also mitosis promoting factors, which is involved in promoting the M phase.

Each of the above cyclin - CDKs are expressed in different stages of cell cycle. During mid-G1 cyclin D and CDK4 and 6 are expressed. In late-G1 cyclin E and CDK2 are expressed. In S-Phase cyclin A and CDK2 are expressed and finally in mitotic phase cyclin A, B along with CDK1 are expressed. These are the regulators of the cell cycles along with other proteins and enzymes that are either expressed before or after cell cycle. For example, cell receptor EGF and signalling molecules such as RAS also control and regulate cell cycle progression in animals along with p53 and BCL-2.

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Видео Cell Cycle Regulation | Basics Explained | Hindi канала BaaYo