CORONAVIRUS NUEVA VARIANTE "BRASILEÑA"

CONOCIDA COMO VARIANTE "BRASILEÑA", IMPACTANTE NUEVA CEPA QUE PREOCUPA AL MUNDO
Esta nueva variante del SARS-CoV2 pone en alerta a la comunidad científica. Conocida como P1 o N501Y V.3 , o también ‘’variante Brasilera’’ o ‘’Variante de Manaus’’.
¿Es más grave la infección por esta cepa?
¿Es más contagiosa?
¿Las vacunas protegen contra esta mutación?
¿Si tuvimos COVID19 podemos re infectarnos con esta nueva variante?

Video con fines educativos, dirigido principalmente a personas del área de la salud.

Bibliografía
- World Healt Organization Webinar: SARS-CoV-2 virus mutations and variants 3 February 2021 14:30 – 15:15 CET
- Center for Disease Control and Prevention: Emerging SARS-CoV-2 Variants pdated Jan. 28, 2021
- Center for Disease Control and Prevention: SARS-CoV-2 Variants. Updated Jan. 31, 2021
- Spike E484K mutation in the first SARS-CoV-2 reinfection case confirmed in Brazil, 2020. https://virological.org/t/spike-e484k-mutation-in-the-first-sars-cov-2-reinfection-case-confirmed-in-brazil-2020/584
- SARS-CoV-2 reinfection by the new Variant of Concern (VOC) P.1 in Amazonas, Brazil. https://virological.org/t/sars-cov-2-reinfection-by-the-new-variant-of-concern-voc-p-1-in-amazonas-brazil/596
- Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings nCoV-2019 Genomic Epidemiology https://virological.org/t/genomic-characterisation-of-an-emergent-sars-cov-2-lineage-in-manaus-preliminary-findings/586
- National Institute of Infectious Diseases. Japan. Brief report: new variant strain of SARS-CoV-2 identified in travelers from Brazil. 2021 Jan 21 [cited 2021 Jan 27]. https://www.niid.go.jp/niid/images/epi/corona/covid19-33-en-210112.pdf
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- Novel variant 501Y.V2 with triple spike receptor binding site substitutions https://www.gisaid.org/
- Mahase Elisabeth. Covid-19: What new variants are emerging and how are they being investigated? BMJ 2021; 372 :n158
- Comprehensive mapping of mutations to the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human serum antibodies Allison J. Greaney, Andrea N. Loes, Katharine H.D. Crawford, Tyler N. Starr, Keara D. Malone, Helen Y. Chu, Jesse D. Bloom bioRxiv 2020.12.31.425021; doi: https://doi.org/10.1101/2020.12.31.425021
- mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants Kai Wu, Anne P. Werner, Juan I. Moliva, Matthew Koch, Angela Choi, Guillaume B. E. Stewart-Jones, Hamilton Bennett, Seyhan Boyoglu-Barnum, Wei Shi, Barney S. Graham, Andrea Carfi, Kizzmekia S. Corbett, Robert A. Seder, Darin K. Edwards bioRxiv 2021.01.25.427948; doi: https://doi.org/10.1101/2021.01.25.427948
- Science 22 Jan 2021: Vol. 371, Issue 6527, pp. 329-330 DOI: 10.1126/science.371.6527.329
- Impact of SARS-CoV-2 B.1.1.7 Spike variant on neutralisation potency of sera from individuals vaccinated with Pfizer vaccine BNT162b2 medRxiv preprint doi https://doi.org/10.1101/2021.01.19.21249840
- Volz E, Hill V, McCrone J, et al. Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity. Cell 2021; 184(64-75). doi: https://doi.org/10.1016/j.cell.2020.11.020external icon.
- Bin Zhou, Tran Thi Nhu Thao, Donata Hoffmann, et al. SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility bioRxiv 2020.10.27 doi: https://doi.org/10.1101/2020.10.27.357558external icon.

#COVID_19 #Stayhome #Coronavirus #Brasil #Manaus

Видео CORONAVIRUS NUEVA VARIANTE "BRASILEÑA" канала Dr. Veller