Vitamin-D ନିର୍ମାଣରେ କିଡ଼ନୀର ଭୂମିକା ▶Details about Kidney Diseases | Dr. Avijeet Dash #healthguardian

Yes, the kidneys play a crucial role in converting vitamin-D into its active form, calcitriol (1,25-dihydroxyvitamin D), which is essential for calcium and phosphorus metabolism, bone health, and other functions.
Here's a more detailed explanation:
Vitamin D Metabolism:
Vitamin D is either obtained through diet or synthesized in the skin upon exposure to sunlight.
Liver's Role:
The liver converts vitamin D into 25-hydroxyvitamin D (25(OH)D), the main storage form of vitamin D.
Kidney's Role:
The kidneys then further convert 25(OH)D into the active form, calcitriol (1,25(OH)2D), using the enzyme 1-alpha-hydroxylase.
Importance of Calcitriol:
Calcitriol is crucial for:
Calcium and Phosphorus Metabolism: It helps regulate the absorption of calcium and phosphorus from the gut and their deposition in bones.
Bone Health: It's essential for maintaining strong bones and preventing osteoporosis.
Other Functions: Calcitriol plays a role in immune function, muscle function, and other processes.
Kidney Disease and Vitamin D:
In kidney disease, the kidneys' ability to activate vitamin D is impaired, leading to vitamin D deficiency and related problems like bone disease and other complications.
Other Tissues:
While the kidney is the primary site for the activation of vitamin D, other tissues like the skin, macrophages, and cells of the vasculature can also produce 1,25-dihydroxyvitamin D locally.
🩺
Dr. Kumar Avijeet Dash
Nephrologist (କିଡ଼ନୀ ରୋଗ ବିଶେଷଜ୍ଞ)
Apollo Hospitals, Bhubaneswar

#avijeetdash #healthguardian #kumaravijeet #nephrologist #dravijeet #abhijitkumar #health

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Видео Vitamin-D ନିର୍ମାଣରେ କିଡ଼ନୀର ଭୂମିକା ▶Details about Kidney Diseases | Dr. Avijeet Dash #healthguardian канала Health Guardian