Reconstructing ancient pathogens - discovery of Yersinia pestis in Eurasia 5,000 Years Ago
The bacterium Yersinia pestis is the etiological agent of plague and has caused human pandemics with millions of deaths in historic times. How and when it originated remains contentious. Here, we report the oldest direct evidence of Yersinia pestis identified by ancient DNA in human teeth from Asia and Europe dating from 2,800 to 5,000 years ago. By sequencing the genomes, we find that these ancient plague strains are basal to all known Yersinia pestis. We find the origins of the Yersinia pestis lineage to be at least two times older than previous estimates. We also identify a temporal sequence of genetic changes that lead to increased virulence and the emergence of the bubonic plague. Our results show that plague infection was endemic in the human populations of Eurasia at least 3,000 years before any historical recordings of pandemics. Our findings open the possibility of identifying other blood borne pathogens directly from human remains (See S. Rasmussen, M. E. Allentoft, K. Nielsen, L. Orlando, M. Sikora, K.-G. Sjögren …
E. Willerslev (2015). Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago. Cell, 163:571–582).
Author - PhD Rasmussen, Simon, Technical University of Denmark, Kgs. Lyngby, Denmark (Presenting author)
Co-author(s) - Allentoft, Morten, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Nielsen, Kasper, Technical University of Denmark, Kgs. Lyngby, Denmark
Co-author(s) - Orlando, Ludovic, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Sikora, Martin, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Sjögren, Karl-Göran, University of Gothenburg, Gothenburg, Sweden
Co-author(s) - Kristiansen, Kristian, University of Gothenburg, Gothenburg, Sweden
Co-author(s) - Willerslev, Eske, Center for Geogenetics, Copenhagen, Denmark
Видео Reconstructing ancient pathogens - discovery of Yersinia pestis in Eurasia 5,000 Years Ago канала Recording Archaeology
E. Willerslev (2015). Early Divergent Strains of Yersinia pestis in Eurasia 5,000 Years Ago. Cell, 163:571–582).
Author - PhD Rasmussen, Simon, Technical University of Denmark, Kgs. Lyngby, Denmark (Presenting author)
Co-author(s) - Allentoft, Morten, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Nielsen, Kasper, Technical University of Denmark, Kgs. Lyngby, Denmark
Co-author(s) - Orlando, Ludovic, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Sikora, Martin, Center for Geogenetics, Copenhagen, Denmark
Co-author(s) - Sjögren, Karl-Göran, University of Gothenburg, Gothenburg, Sweden
Co-author(s) - Kristiansen, Kristian, University of Gothenburg, Gothenburg, Sweden
Co-author(s) - Willerslev, Eske, Center for Geogenetics, Copenhagen, Denmark
Видео Reconstructing ancient pathogens - discovery of Yersinia pestis in Eurasia 5,000 Years Ago канала Recording Archaeology
Показать
Комментарии отсутствуют
Информация о видео
Другие видео канала
Moving Around and Settling Down – Reconstructing Palaeolithic Land Use with GISWAC Indigenous Plenary - Dorothy LippertMudlarking on the Thames ForeshoreArchaeological sequence diagrams, directed graphs and Bayesian chronological models,Geometric morphometrics, visual perception of similarity, gestalt principles and creating groupsEvidence of early settlement at Honeyberry, RattrayBooms and Bombs- Situating Breath of the Wild within the “Jomon Boom” trendThree-dimensional documentation, reconstruction and visualization of site stratigraphyExperimental Archaeology: A Conceptual Bridge?The Big Data Challenge. Integrative Big Data Approaches towards a Hybrid ArchaeologySerial, fast and low cost 3D pottery on site documentationApplication of object detection and semantic segmentation in structure from motion mappings of minesBirnam & Dunkeld Historical SocietyThe Small IslesEducation or fun? Creating video games to promote archaeological thinkingProfileAAR – a small tool helping to rectify archaeological profiles in QGISFantasy Worlds / Fantastic LabsFAME Webinar: Curatorial practice: accessioning, collections care, accessibility.Irish Bronze Age Cinerary UrnsHow to manage archaeological archives - SMART WorkshopA Neolithic pit-defined enclosure and Roman field ovens at Alyth Substation: in spring 2021