An Introduction to Spike Sorting
Jai Bhagat and Caroline Moore-Kochlacs, MIT
Description: In in vivo animal models, neuroscience experiments in electrophysiology are commonly performed with the use of extracellular electrodes that get implanted in the cell layer of specific brain regions of interest. These electrodes record voltage traces, and capture the occurrence of putative action potentials when there is a “spike” in the voltage trace. Each spike’s source (a putative, single neuron) is unknown to the experimenter at the time of the recording, so “spike sorting” is an analysis that is performed to group spikes together based on some set of shared characteristics. Each grouping (or cluster) of spikes is assumed to come from the same neuron. This tutorial will start with a quick introduction to common ephys recording set-ups. We will then give an overview of the spike sorting workflow, from filtering the raw voltage traces to assessing the quality of the final spike clusters. The tutorial will end with the participants performing hands-on spike sorting in MATLAB.
(Optional) Introductory Reading: http://www.scholarpedia.org/article/Spike_sorting
Видео An Introduction to Spike Sorting канала MITCBMM
Description: In in vivo animal models, neuroscience experiments in electrophysiology are commonly performed with the use of extracellular electrodes that get implanted in the cell layer of specific brain regions of interest. These electrodes record voltage traces, and capture the occurrence of putative action potentials when there is a “spike” in the voltage trace. Each spike’s source (a putative, single neuron) is unknown to the experimenter at the time of the recording, so “spike sorting” is an analysis that is performed to group spikes together based on some set of shared characteristics. Each grouping (or cluster) of spikes is assumed to come from the same neuron. This tutorial will start with a quick introduction to common ephys recording set-ups. We will then give an overview of the spike sorting workflow, from filtering the raw voltage traces to assessing the quality of the final spike clusters. The tutorial will end with the participants performing hands-on spike sorting in MATLAB.
(Optional) Introductory Reading: http://www.scholarpedia.org/article/Spike_sorting
Видео An Introduction to Spike Sorting канала MITCBMM
Показать
Комментарии отсутствуют
Информация о видео
Другие видео канала
Large-scale recording of local field and action potentials, Prof. György BuzsákiOnline Neural Data Processing with Plexon OmniPlex: Referencing, Sorting and Online ManipulationPrincipal Component Analysis (PCA) clearly explained (2015)An Introduction to LSTMs in TensorflowThe Action PotentialCognitive Neuroscience at Dartmouth - Spike timing, sequences, and model-based predictionTheoretical issues in deep networks [video]Electophysiology: Patch clamp methodWhole cell patch clamp electrophysiologyFunctional Imaging of the Human Brain: A Window into the Organization of the Human MindLocal field potentials for brain machine interfaces | Nur AhmadiA Computational Explanation for Domain Specificity in the Human Visual SystemA simple spiking neuron model: biological backgroundPatch clamp technique method | electrophysiology technique6.4 In vivo electrophysiologyUsing population decoding to understand neural content and codingSpike2 tutorials: Setting threshold triggers for spike sorting (WMtriggers)Hines, Michael - Using Neuron + Python for parallel simulationInferior temporal cortex potential cortical precursor of orthographic processing in untrained monkeyFundamentals of neuronal oscillations and synchrony