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Multiomics Data for Cancer Diagnosis (AlphaCare: Episode 3)

The amount of molecular biology datasets available are growing exponentially every month. Multiomics consist of all the layers of the molecular biome; the genome, epigenome, transcriptome, proteome, and metabolome. In this episode, we're going to learn how each of the layers of the molecular biology stack work, and then look at 3 different real world use cases for Cancer patients (diagnostic, prognostic, and predictive) using open-source python code on GitHub. Then we'll look at how a Generative Adversarial Network can be used to generate synthetic genomic data to battle imbalanced classes. Enjoy!

Big thanks to RapidAPI for sponsoring this video series:
https://rapidapi.com/hub?utm_source=Siraj-Raval&utm_medium=DevRel&utm_campaign=DevRel

Omics Datasets:
https://www.omicsdi.org/search

More Omics Datasets:
https://www.ncbi.nlm.nih.gov/geo/browse/?view=series&display=20&zsort=samples

Code Credits:
Example 1 (CITE-Seq autoencoder prognosis):
https://github.com/naity/citeseq_autoencoder

Example 2 (UMAP diagnosis):
https://github.com/NikolayOskolkov/UMAPDataIntegration

Example 3 (AlphaFold Protein Folding Prediction:
https://alphafold.ebi.ac.uk/
https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/AlphaFold2.ipynb#scrollTo=KK7X9T44pWb7

Example 4 (GAN for Genomic Data Synthesis):
https://github.com/Unique-Divine/GANs-for-Genomics

Generative Biome HTML:
https://github.com/marpi/biomes

More Learning Resources:

AlphaCare Episode 1:
https://www.youtube.com/watch?v=fGv6VmfGMLc

AlphaCare Episode 2:
https://www.youtube.com/watch?v=PrqdEJZOrWE&t=10s

AlphaFold Tutorial:
https://www.youtube.com/watch?v=GQH-zWUylPY

How I Gamify Learning:
https://www.youtube.com/watch?v=nH85q7gC8uw

Learn Machine Learning in 3 months:
https://www.youtube.com/watch?v=Cr6VqTRO1v0

Multiomics Paper 1:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003173/

Multiomics Paper 2:
https://www.frontiersin.org/articles/10.3389/fgene.2020.610798/full

Follow me:

INSTAGRAM:
https://www.instagram.com/sirajraval/

TWITTER:
https://twitter.com/sirajraval

FACEBOOK:
https://www.facebook.com/sirajologyyy

LINKEDIN:
https://www.linkedin.com/in/sirajraval/

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Видео Multiomics Data for Cancer Diagnosis (AlphaCare: Episode 3) канала Siraj Raval
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16 октября 2021 г. 2:45:26
00:10:57
Яндекс.Метрика