Programmed Bacteria for Cancer Immunotherapy
The emerging field of synthetic biology—designing new biological components and systems—is revolutionizing medicine. Through the genetic programming of living cells, researchers are creating engineered systems that intelligently sense and respond to diverse environments, leading to more specific and effective solutions in comparison to current molecular-based therapeutics.
Teaming up with the Columbia University Irving Medical Center (CUIMC), Columbia Engineering has addressed this challenge by engineering a strain of non-pathogenic bacteria that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. The therapy led not only to complete tumor regression in a mouse model of lymphoma, but also significant control of distant, uninjected tumor lesions. Their findings are published in Nature Medicine.
Видео Programmed Bacteria for Cancer Immunotherapy канала Columbia Engineering
Teaming up with the Columbia University Irving Medical Center (CUIMC), Columbia Engineering has addressed this challenge by engineering a strain of non-pathogenic bacteria that can colonize solid tumors in mice and safely deliver potent immunotherapies, acting as a Trojan Horse that treats tumors from within. The therapy led not only to complete tumor regression in a mouse model of lymphoma, but also significant control of distant, uninjected tumor lesions. Their findings are published in Nature Medicine.
Видео Programmed Bacteria for Cancer Immunotherapy канала Columbia Engineering
Показать
Комментарии отсутствуют
Информация о видео
Другие видео канала
Eitan Grinspun, Professor Computer ScienceEngineering for Humanity: CREATIVEIntroduction to Industrial Engineering and Operations ResearchChristine Hendon: Designing optical tools for medicineAsk Us Anything: Andrew Smyth HighlightsGiving Day: Mike Massimino for Columbia EngineeringA Self-Reliant RobotDean Peña-Mora Details Proposal for Columbia's New Engineering and Applied Sciences CampusAsk Us Anything: Toni Pitassi HighlightsCAIT EXCERPT: Do we need to understand AI to trust it?Reunion Lecture: Crisis Response and EthicsGiving Day: Columbia EngineeringCLUB LIFE: Columbia University Formula SAEEitan Grinspun - TEDxColumbiaEngineering - 11/29/11Ask Us Anything: Lorenzo Polvani HighlightsThe Nanostructure Problem: Simon Billinge at Brookhaven National LabsThe Columbia Electrochemical Energy Center LaunchJake Porway - TEDxColumbiaEngineering - 11/29/11Taking Our Mission into the New DecadeEngineering Icons: Mike Massimino IntroductionWelcome to the Columbia Electrochemical Energy Center