The Reason Prescription Drugs Will Never Be Developed Fast!
Hank Green talks with us about why research and development make the prescription drug development process long... understandably.
Use code SCISHOW to get $5 off your delicious, healthy Magic Spoon cereal by clicking this link: https://magicspoon.thld.co/scishow_0322
It can potentially take decades for medications to reach pharmacy shelves, but why? We take a deep dive into the creation of a cancer treatment to explain the process.
Hosted by: Hank Green
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Tomás Lagos González, Sam Lutfi. Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Jason A Saslow, Nazara, Tom Mosner, Ash, Eric Jensen, Jeffrey Mckishen, Matt Curls, Alex Hackman, Christopher R Boucher, Piya Shedden, Jeremy Mysliwiec, charles george, Chris Peters, Adam Brainard, Dr. Melvin Sanicas, Harrison Mills, Silas Emrys, Alisa Sherbow
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow
----------
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354961/
https://www.nature.com/articles/s41586-019-1694-1
https://www.fda.gov/news-events/press-announcements/fda-approves-first-targeted-therapy-lung-cancer-mutation-previously-considered-resistant-drug
https://www.cell.com/the-innovation/pdf/S2666-6758(20)30035-7.pdf
https://pubmed.ncbi.nlm.nih.gov/26739882/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216832/
https://www.amgen.com/newsroom/press-releases/2021/01/amgens-investigational-kras-g12c-inhibitor-sotorasib-demonstrated-rapid-deep-and-durable-responses-in-previously-treated-patients-with-advanced-nonsmall-cell-lung-cancer
https://www.cell.com/cell/fulltext/S0092-8674(18)30041-2?_return
https://directorsblog.nih.gov/2018/02/13/kras-targeted-cancer-strategy-shows-early-promise/
https://www.science.org/content/article/two-new-drugs-finally-hit-undruggable-cancer-target-providing-hope-treatments
MOLECULE STRUCTURES
Compound 12 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u5_hi-res.gif
ARS-853 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u7_hi-res.gif
ARS-1620 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u8_hi-res.gif
ARS-510 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u10_hi-res.gif
MRTX849 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u13_hi-res.gif
Images
https://www.storyblocks.com/video/stock/rack-focus-from-scientist-digital-tablet-pc-to-researcher-desk-working-on-a-computer-with-advanced-scan-bbej_kdjrjx32gd8i
https://www.istockphoto.com/photo/testing-drugs-and-vaccine-on-mice-gm1227553397-362087698
https://www.istockphoto.com/photo/laboratory-mouse-gm172267826-3711102
https://commons.wikimedia.org/wiki/File:Freezed_XRD.jpg
https://www.mdpi.com/1422-0067/21/18/6806/htm
https://www.istockphoto.com/vector/utility-knife-line-style-icon-design-gm1156138646-314996692
https://www.istockphoto.com/photo/scientist-carefully-carrying-matured-cell-to-another-plate-conducting-research-gm879831370-245197680
https://www.istockphoto.com/photo/medical-science-laboratory-with-diverse-multi-ethnic-team-of-biotechnology-gm1293772957-388051705
https://commons.wikimedia.org/wiki/File:KRAS_protein_3GFT.png
https://www.storyblocks.com/video/stock/abstrat-industrial-clock-gears-2-sw-amfntbk3z8wb2m
https://www.istockphoto.com/photo/skin-gm56961296-29923876
https://commons.wikimedia.org/wiki/File:Oncogenes_illustration.jpg
https://www.storyblocks.com/video/stock/macro-shot-of-lab-tech-placing-a-blood-sample-on-a-bightly-lit-microscope-slide-syvn75mkpkcdpmjki
https://www.istockphoto.com/photo/microscope-with-lab-glassware-gm909908830-250604421
https://commons.wikimedia.org/wiki/File:FDA_Sign_%26_Bldg_21_at_Entrance_(5204602349).jpg
https://www.istockphoto.com/photo/asian-senior-elderly-male-patient-consult-with-physician-nurse-at-nursing-home-care-gm1317922601-405208908
https://www.istockphoto.com/photo/efficient-pharmacy-operations-thanks-to-teamwork-gm1036131880-277355254
https://www.istockphoto.com/photo/this-is-how-i-get-through-the-day-gm1135088881-301842519
https://www.istockphoto.com/photo/theres-always-something-waiting-to-be-discovered-gm1027139762-275404932
https://www.istockphoto.com/photo/theres-always-something-waiting-to-be-discovered-gm1027139762-275404932
Видео The Reason Prescription Drugs Will Never Be Developed Fast! канала SciShow
Use code SCISHOW to get $5 off your delicious, healthy Magic Spoon cereal by clicking this link: https://magicspoon.thld.co/scishow_0322
It can potentially take decades for medications to reach pharmacy shelves, but why? We take a deep dive into the creation of a cancer treatment to explain the process.
Hosted by: Hank Green
SciShow is on TikTok! Check us out at https://www.tiktok.com/@scishow
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Tomás Lagos González, Sam Lutfi. Bryan Cloer, Christoph Schwanke, Kevin Bealer, Jacob, Jason A Saslow, Nazara, Tom Mosner, Ash, Eric Jensen, Jeffrey Mckishen, Matt Curls, Alex Hackman, Christopher R Boucher, Piya Shedden, Jeremy Mysliwiec, charles george, Chris Peters, Adam Brainard, Dr. Melvin Sanicas, Harrison Mills, Silas Emrys, Alisa Sherbow
----------
Looking for SciShow elsewhere on the internet?
SciShow Tangents Podcast: https://scishow-tangents.simplecast.com/
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Instagram: http://instagram.com/thescishow
#SciShow
----------
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354961/
https://www.nature.com/articles/s41586-019-1694-1
https://www.fda.gov/news-events/press-announcements/fda-approves-first-targeted-therapy-lung-cancer-mutation-previously-considered-resistant-drug
https://www.cell.com/the-innovation/pdf/S2666-6758(20)30035-7.pdf
https://pubmed.ncbi.nlm.nih.gov/26739882/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216832/
https://www.amgen.com/newsroom/press-releases/2021/01/amgens-investigational-kras-g12c-inhibitor-sotorasib-demonstrated-rapid-deep-and-durable-responses-in-previously-treated-patients-with-advanced-nonsmall-cell-lung-cancer
https://www.cell.com/cell/fulltext/S0092-8674(18)30041-2?_return
https://directorsblog.nih.gov/2018/02/13/kras-targeted-cancer-strategy-shows-early-promise/
https://www.science.org/content/article/two-new-drugs-finally-hit-undruggable-cancer-target-providing-hope-treatments
MOLECULE STRUCTURES
Compound 12 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u5_hi-res.gif
ARS-853 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u7_hi-res.gif
ARS-1620 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u8_hi-res.gif
ARS-510 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u10_hi-res.gif
MRTX849 https://pubs.rsc.org/image/article/2020/MD/d0md00096e/d0md00096e-u13_hi-res.gif
Images
https://www.storyblocks.com/video/stock/rack-focus-from-scientist-digital-tablet-pc-to-researcher-desk-working-on-a-computer-with-advanced-scan-bbej_kdjrjx32gd8i
https://www.istockphoto.com/photo/testing-drugs-and-vaccine-on-mice-gm1227553397-362087698
https://www.istockphoto.com/photo/laboratory-mouse-gm172267826-3711102
https://commons.wikimedia.org/wiki/File:Freezed_XRD.jpg
https://www.mdpi.com/1422-0067/21/18/6806/htm
https://www.istockphoto.com/vector/utility-knife-line-style-icon-design-gm1156138646-314996692
https://www.istockphoto.com/photo/scientist-carefully-carrying-matured-cell-to-another-plate-conducting-research-gm879831370-245197680
https://www.istockphoto.com/photo/medical-science-laboratory-with-diverse-multi-ethnic-team-of-biotechnology-gm1293772957-388051705
https://commons.wikimedia.org/wiki/File:KRAS_protein_3GFT.png
https://www.storyblocks.com/video/stock/abstrat-industrial-clock-gears-2-sw-amfntbk3z8wb2m
https://www.istockphoto.com/photo/skin-gm56961296-29923876
https://commons.wikimedia.org/wiki/File:Oncogenes_illustration.jpg
https://www.storyblocks.com/video/stock/macro-shot-of-lab-tech-placing-a-blood-sample-on-a-bightly-lit-microscope-slide-syvn75mkpkcdpmjki
https://www.istockphoto.com/photo/microscope-with-lab-glassware-gm909908830-250604421
https://commons.wikimedia.org/wiki/File:FDA_Sign_%26_Bldg_21_at_Entrance_(5204602349).jpg
https://www.istockphoto.com/photo/asian-senior-elderly-male-patient-consult-with-physician-nurse-at-nursing-home-care-gm1317922601-405208908
https://www.istockphoto.com/photo/efficient-pharmacy-operations-thanks-to-teamwork-gm1036131880-277355254
https://www.istockphoto.com/photo/this-is-how-i-get-through-the-day-gm1135088881-301842519
https://www.istockphoto.com/photo/theres-always-something-waiting-to-be-discovered-gm1027139762-275404932
https://www.istockphoto.com/photo/theres-always-something-waiting-to-be-discovered-gm1027139762-275404932
Видео The Reason Prescription Drugs Will Never Be Developed Fast! канала SciShow
Показать
Комментарии отсутствуют
Информация о видео
Другие видео канала
What Happens to My Wool Sweater in the Washer?Your Bones Do More Than You ThinkWhy Don't Sleeping Bats Fall Down?Tiny Extremophiles Living in Rocks!What Ventilators Taught Us About BreathingWhy Does Spicy Taste 'Hot' and Minty Taste 'Cool'?Why Are Paper Cuts So Painful?Why Do Itches Make You Chase Them?Cephalopods Have a Totally Wild Way of AdaptingWhy Can Applesauce Replace Butter? And Oil? And Eggs?Why Do Things Look Darker When They're Wet?An Alzheimer’s Drug That Doesn’t Treat Alzheimer’s?The Wasp That Reprograms SpidersNo Hips, No Problem: Better Hip Replacements From SnakesWhy Do Antidepressants Cause Brain Zaps?The Little Apple of DeathWhy Do Spiders Curl Up When They Die?The Real Reason Dogs Kick When You Scratch ThemWhy Does Glitter Stick to Everything?Why Do I Have Varicose Veins?Experts "Stunned" by Organ Death Reversal | SciShow News