Variome

Happy Birthday! You have got a unique genome from your parents – three point two billions pairs of nucleotides! Nucleotides are like notes in a melody – all of them must be on their places and if they are not – you can hear a false. This error in genome is named mutation and unfortunately causes hereditary diseases development. But now a pianist does not make a mistake and plays other notes, thus the melody acquires interesting features! In genetic like in music it is named variation or SNP (single nucleotide polymorphism, snip). There are around a hundred millions of snips that is actually not so many knowing that our genome comprises of three point two billions pairs of nucleotides. So only in three-point two percents of sites other letters could be placed and we are identical by the rest having Homo sapiens genotype. But we are different, that is obvious. All this peoples’ diversity in physical, biochemical, intellectual features is determined by combinations of hundred millions of variations. Three point two percents and all the variety of peoples! Hard to believe, isn’t it?

Видео Variome канала Molecula club