Coronavirus Q&A: Critical Care Update

COVID-19 Critical Care Update with Maurizio Cecconi, MD of Humanitas University in Milan and Derek C. Angus, MD, MPH of the University of Pittsburgh. Recorded on June 8, 2020.

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Topics discussed in this interview:
0:00 Introduction
1:34 Anything new about epidemiology of COVID-19? What's the major risk characteristics, risk factors? What's the mortality look like in the intensive care unit?
4:33 What is the mortality rate in the ICU run by Dr Angus in Pittsburgh?
5:58 Is smoking or asthma is protective?
11:45 Where are we on respiratory support? High-flow oxygen, prone positioning, preventing intubation? Is early intubation better than late intubation?
14:52 Prone positioning prior to intubation?
16:23 Approach to respiratory support
21:22 Are there phenotypes and should phenotypes drive therapy? (Treatments)
30:13 Is it going to take more than one drug to really reduce mortality? Is it convalescent plasma and steroids? Is it Tocilizumab and steroids?
33:13 Do you think it's some form of two drugs? Is it earlier treatment with some drug regimen?
35:19 Convalescent plasma as a treatment as compared to Remdesivir?
37:19 Does the morbidity associated with COVID-19, following being in the ICU look different to you than any other frail, elderly individual who is in the ICU and is either intubated or not? Do they need a different type of post-ICU care?
42:17 From a critical care standpoint, what have been the biggest surprises from this pandemic? What scientific questions do we still need to answer?
50:27 Closing notes

Видео Coronavirus Q&A: Critical Care Update канала JAMA Network