Here's What DNA Really Looks Like
There’s more to DNA than just the double helix we know and love: under some conditions this familiar molecule can take on unfamiliar forms, each of which can have a different impact on our health.
Hosted by: Hank Green
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Sources:
General overviews of alternate DNA structures:
https://www.intechopen.com/books/dna-replication-current-advances/dna-structure-alphabet-soup-for-the-cellular-soul
https://www.ncbi.nlm.nih.gov/books/NBK6545/
http://people.bu.edu/mfk/restricted566/dnastructure.pdf
B-DNA and history of the double helix:
https://www.nature.com/scitable/topicpage/discovery-of-dna-structure-and-function-watson-397/
A-DNA:
https://journals.iucr.org/q/issues/1953/08-09/00/a00979/a00979.pdf
Z-DNA:
https://www.nature.com/articles/s42003-018-0237-x
H-DNA:
https://www.pnas.org/content/pnas/101/37/13448.full.pdf
G-quadruplexes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516791/
Image Sources:
https://commons.wikimedia.org/wiki/File:Base_pair_GC.svg
https://commons.wikimedia.org/wiki/File:Base_pair_AT.svg
https://commons.wikimedia.org/wiki/File:DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:A-DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:Z-DNA_orbit_animated.gif
https://www.istockphoto.com/vector/dna-gm477462523-36133444
https://www.istockphoto.com/photo/chromatin-strand-and-isolated-nucleosome-dna-histones-gm1169905740-323575931
https://commons.wikimedia.org/wiki/File:A-B-Z-DNA_Side_View.png
https://commons.wikimedia.org/wiki/File:Adna3.ogv
https://commons.wikimedia.org/wiki/File:0323_DNA_Replication.jpg
https://commons.wikimedia.org/wiki/File:DNA_replication_split.svg
https://www.istockphoto.com/photo/abstract-glittering-dna-helix-with-depth-of-field-over-dark-space-background-gm1201193016-344376611
https://commons.wikimedia.org/wiki/File:TriplexDNA(1BWG).png
https://www.istockphoto.com/photo/the-fracture-of-dna-molecular-gm450571643-24790953
https://www.istockphoto.com/photo/illustration-of-a-damaged-ribonucleic-acid-or-dna-strand-gm923218260-253424716
https://www.istockphoto.com/photo/yellow-and-blue-shoelace-gm120499022-15977723
https://www.istockphoto.com/photo/telomere-gm670202484-122541287
https://www.istockphoto.com/photo/chromosomes-gm173851340-8968775
https://commons.wikimedia.org/wiki/File:Guanin.svg
https://commons.wikimedia.org/wiki/File:G-quadruplex.svg
https://commons.wikimedia.org/wiki/File:Telomer-structure.gif
https://commons.wikimedia.org/wiki/File:Basic_units_of_chromatin_structure.svg
https://commons.wikimedia.org/wiki/File:Cytosin.svg
https://commons.wikimedia.org/wiki/File:RNA_i-motif.gif
https://commons.wikimedia.org/wiki/File:Holliday_junction_coloured.png
Видео Here's What DNA Really Looks Like канала SciShow
Hosted by: Hank Green
SciShow has a spinoff podcast! It's called SciShow Tangents. Check it out at http://www.scishowtangents.org
----------
Support SciShow by becoming a patron on Patreon: https://www.patreon.com/scishow
----------
Huge thanks go to the following Patreon supporters for helping us keep SciShow free for everyone forever:
Bd_Tmprd, Harrison Mills, Jeffrey Mckishen, James Knight, Christoph Schwanke, Jacob, Matt Curls, Sam Buck, Christopher R Boucher, Eric Jensen, Lehel Kovacs, Adam Brainard, Greg, Ash, Sam Lutfi, Piya Shedden, KatieMarie Magnone, Scott Satovsky Jr, Charles Southerland, charles george, Alex Hackman, Chris Peters, Kevin Bealer
----------
Looking for SciShow elsewhere on the internet?
Facebook: http://www.facebook.com/scishow
Twitter: http://www.twitter.com/scishow
Tumblr: http://scishow.tumblr.com
Instagram: http://instagram.com/thescishow
----------
Sources:
General overviews of alternate DNA structures:
https://www.intechopen.com/books/dna-replication-current-advances/dna-structure-alphabet-soup-for-the-cellular-soul
https://www.ncbi.nlm.nih.gov/books/NBK6545/
http://people.bu.edu/mfk/restricted566/dnastructure.pdf
B-DNA and history of the double helix:
https://www.nature.com/scitable/topicpage/discovery-of-dna-structure-and-function-watson-397/
A-DNA:
https://journals.iucr.org/q/issues/1953/08-09/00/a00979/a00979.pdf
Z-DNA:
https://www.nature.com/articles/s42003-018-0237-x
H-DNA:
https://www.pnas.org/content/pnas/101/37/13448.full.pdf
G-quadruplexes:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516791/
Image Sources:
https://commons.wikimedia.org/wiki/File:Base_pair_GC.svg
https://commons.wikimedia.org/wiki/File:Base_pair_AT.svg
https://commons.wikimedia.org/wiki/File:DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:A-DNA_orbit_animated.gif
https://commons.wikimedia.org/wiki/File:Z-DNA_orbit_animated.gif
https://www.istockphoto.com/vector/dna-gm477462523-36133444
https://www.istockphoto.com/photo/chromatin-strand-and-isolated-nucleosome-dna-histones-gm1169905740-323575931
https://commons.wikimedia.org/wiki/File:A-B-Z-DNA_Side_View.png
https://commons.wikimedia.org/wiki/File:Adna3.ogv
https://commons.wikimedia.org/wiki/File:0323_DNA_Replication.jpg
https://commons.wikimedia.org/wiki/File:DNA_replication_split.svg
https://www.istockphoto.com/photo/abstract-glittering-dna-helix-with-depth-of-field-over-dark-space-background-gm1201193016-344376611
https://commons.wikimedia.org/wiki/File:TriplexDNA(1BWG).png
https://www.istockphoto.com/photo/the-fracture-of-dna-molecular-gm450571643-24790953
https://www.istockphoto.com/photo/illustration-of-a-damaged-ribonucleic-acid-or-dna-strand-gm923218260-253424716
https://www.istockphoto.com/photo/yellow-and-blue-shoelace-gm120499022-15977723
https://www.istockphoto.com/photo/telomere-gm670202484-122541287
https://www.istockphoto.com/photo/chromosomes-gm173851340-8968775
https://commons.wikimedia.org/wiki/File:Guanin.svg
https://commons.wikimedia.org/wiki/File:G-quadruplex.svg
https://commons.wikimedia.org/wiki/File:Telomer-structure.gif
https://commons.wikimedia.org/wiki/File:Basic_units_of_chromatin_structure.svg
https://commons.wikimedia.org/wiki/File:Cytosin.svg
https://commons.wikimedia.org/wiki/File:RNA_i-motif.gif
https://commons.wikimedia.org/wiki/File:Holliday_junction_coloured.png
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