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Subgroup or noise? TOPCAT regional split #Shorts
Spironolactone failed in HFpEF (TOPCAT NEJM 2014, n=3,445, HR 0.89 NS). Pre-specified regional split: Americas HR 0.82, Russia+Georgia HR 1.10. Eligibility audits flagged the latter. Stats-method: two p under 0.05 in different subgroups is not effect modification. Test the interaction term. ICEMAN 8 questions for credibility. Pitt NEJM 2014 PMID 24716680. https://mahmood726-cyber.github.io/allmeta/ #Shorts
Видео Subgroup or noise? TOPCAT regional split #Shorts канала 786-MIII Meta-analysis
Видео Subgroup or noise? TOPCAT regional split #Shorts канала 786-MIII Meta-analysis
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