Rosuvastatin Review (Crestor) - Everything you need to know! - Doctor Explains

In this video we will cover everything you need to know about Rosuvastatin, also known as Crestor. We will discuss how and when to use it, we will cover its side effects, dosage and much, much more.

You can find more useful videos on cardiovascular diseases and their treatments here:
https://www.youtube.com/playlist?list=PLaG3Bo3L0gX4RW4KCNLMonBoVENz-SKM_

Generic name: Rosuvastatin.
Brand names: Crestor and Ezallor.
Available as tablets and chewable tablets.

How to use it?
- Tablet: just swallow it whole with half a glass of water.
- Chewable tablet: just take the tablets and chew on it until it dissolves. If you want to you can also swallow this tablet whole.
It is best to take this medicine at fixed times. This will make you less likely to forget a dose.

When to use it?
Rosuvastatin is part of a group of drugs called Statins. They inhibit the enzyme HMG-CoA reductase, which normally plays an essential role in the synthesis of cholesterol in the liver. This lowers the circulating LDL, the total cholesterol and increased HDL-cholesterol.
Therefore Rosuvastatin can be used to treat a high cholesterol, familial hypercholesterolemia and it can be used to prevent cardiovascular disease.

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms. Therefore always use the precise amount and frequency your doctor prescribed you.
- However, when treating adults most doctors will start with an initial dose of 5–10 mg 1×/day, if necessary your doctor might double your dose every 4 weeks up to a maximum dose of 40 mg 1x/day.

What are the side-effects?
- Common: Abdominal pain, Nausea, Constipation, Muscle pain, Diabetes mellitus, Dizziness and Headache.
- Uncommon: Skin Rash, Itching and Urticaria.
- Rare: changes in your blood values, edema, hypersensitivity reaction, muscle tear and inflammation of the pancreas.
- Very rare: it can cause several severe side effects.

Safety:
- First of all it is safe to drive when using Rosuvastatin.
- However, it rarely can cause liver abnormalities which can be increased with consumption of too much alcohol. Therefore it is often advised to not drink or at most 1 glass a day while using Rosuvastatin.
- Furthermore, Rosuvastatin can have interactions with other drugs your are taking. Always discuss this with your prescribing doctor.
- Lastly, do not use Rosuvastatin while pregnant or while breastfeeding, as it can be dangerous.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

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Literature:
1: Farmacotherapeutisch Kompas. (2022). Rosuvastatine.
2: Apotheek.nl (2022). Rosuvastatine.

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