MTB Finals Series Rheumatology Session 2: All Things Antibodies

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Topic: All things antibodies

Presenter: Dr Lucy Miller

1. Understand the pathophysiology of systemic sclerosis, including its probable causes, characteristics, and symptoms.
2. Differentiate between the two types of systemic sclerosis: limited cutaneous systemic sclerosis and diffuse cutaneous systemic sclerosis.
3. Identify the key investigations to diagnose systemic sclerosis and interpret the associated autoantibodies: antinuclear antibody, anti-centromere, anti-70 and anti RNA poly three antibodies.
4. Describe the management strategies for systemic sclerosis, considering symptom alleviation as well as preventing further deterioration in internal organ involvement.
5. Recognize the potential risks involved in using long courses or high doses of steroids in the treatment of systemic sclerosis.

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