Elizabeth Blackburn (UCSF) Part 1: The Roles of Telomeres and Telomerase
https://www.ibiology.org/genetics-and-gene-regulation/telomerase/
Lecture Overview
Telomerase, a specialized ribonucleprotein reverse transcriptase, is important for long-term eukaryotic cell proliferation and genomic stability, because it replenishes the DNA at telomeres. Thus depending on cell type telomerase partially or completely (depending on cell type) counteracts the progressive shortening of telomeres that otherwise occurs.
Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. Furthermore, recent collaborative studies have shown the relationship between accelerated telomere shortening and life stress and that low telomerase levels are associated with six prominent risk factors for cardiovascular disease.
Видео Elizabeth Blackburn (UCSF) Part 1: The Roles of Telomeres and Telomerase канала Science Communication Lab
Lecture Overview
Telomerase, a specialized ribonucleprotein reverse transcriptase, is important for long-term eukaryotic cell proliferation and genomic stability, because it replenishes the DNA at telomeres. Thus depending on cell type telomerase partially or completely (depending on cell type) counteracts the progressive shortening of telomeres that otherwise occurs.
Telomerase is highly active in many human malignancies, and a potential target for anti-cancer approaches. Furthermore, recent collaborative studies have shown the relationship between accelerated telomere shortening and life stress and that low telomerase levels are associated with six prominent risk factors for cardiovascular disease.
Видео Elizabeth Blackburn (UCSF) Part 1: The Roles of Telomeres and Telomerase канала Science Communication Lab
Показать
Комментарии отсутствуют
Информация о видео
24 марта 2010 г. 5:47:56
00:48:27
Другие видео канала
iBiology and NRMN Live Q&A: Culturally Responsive MentoringErich Jarvis (Duke/HHMI) Part 1: Convergent behavior and brain pathwaysAlexa Sadier (UCLA): Bat Vision EvolutionSiobhan Braybrook (UCLA) 3: Cell Wall Mechanics and Growth: Beyond PlantsAbby Dernburg (UC Berkeley / LBNL / HHMI) Part 2: Chromosome Pairing during MeiosisDavid Botstein Part 2: Connecting Growth Control and Stress ResponseSebastian Lourido (Whitehead Inst. & MIT) 2: Genetic approaches to study Toxoplasma gondiiBench to Bedside: Mesenchymal Stem Cells and ARDS, Part 2 - Michael MatthayRussell DeBose-Boyd (UTSW) 2: Schnyder Corneal Dystrophy: UBIAD1 Regulation of CholesterolJames Haber (Brandeis) 2: Molecular Mechanisms of Repairing a Broken ChromosomeRebecca Christofferson (LSU) 3: Characterizing Understudied Arboviruses: Orthobunyaviruses in RwandaShare Your Research: How to Give a Good Talk Trailer (captioned)iBiology Young Scientist Series 2016 TrailerRuth Lehmann (NYU / HHMI) 2: Establishing Soma-Germline DichotomyGeraldine Seydoux (Johns Hopkins / HHMI) 2: How to Polarize the CytoplasmJoseph Takahashi (UT Southwestern/HHMI) Part 3: Circadian Clocks: Molecular Basis of a ClockRebecca Christofferson (LSU) 1: Mosquito-Borne ArbovirusesA Winding Life Through Science: Virginia Man-Yee LeeAbby Dernburg (UC Berkeley / LBNL / HHMI) Part 3: The Role of Dynein in Chromosome PairingAngelika Amon (MIT and HHMI) Part 2: Effects of Aneuploidy on Cell PhysiologyBench to Bedside: Lifitegrast, pt.1 - The SARcode Story: How to build a biotech company - Tom Gadek